TSH Is a Novel Neuroendocrine Regulator of Selected Keratins in the Human Hair Follicle

    Yuval Ramot, Guoyou Zhang, Tamás Bı́ró, Erika Lisztes, Wolfang Funk, Arieh Ingber, Lutz Langbein, Ralf Paus
    TLDR TSH influences keratin expression in human hair follicles.
    The study explored the role of thyroid-stimulating hormone (TSH) as a neuroendocrine regulator of keratin expression in human hair follicles (HFs). It was found that TSH, along with other hormones like prolactin (PRL) and thyrotropin-releasing hormone (TRH), significantly influenced the expression of selected keratins in HF organ cultures. Despite TSH's role in regulating keratin expression, its overall functions in HF biology were not fully understood. The research highlighted the complex neuroendocrine regulation of keratin expression, suggesting potential pathways for influencing hair growth and follicle function.
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