51 citations
,
November 1988 in “The Journal of Clinical Endocrinology & Metabolism” This study found that serum 3 alpha-Adiol-G levels in men are significantly associated with chest hair density and acne, indicating its role in reflecting androgen activity in peripheral tissues.
11 citations
,
September 2015 in “Theriogenology” Testosterone boosts fluid and electrolyte secretion in seminal vesicles, aiding sperm function.
9 citations
,
November 1980 in “Geburtshilfe und Frauenheilkunde” In this study, prolonged intravenous Fenoterol infusion was associated with intensive hair growth in most patients, although hormonal changes typically linked to such effects were not observed.
3 citations
,
June 2021 in “Frontiers in genetics” This study found that STAT3 directly inhibited the activity of the sheep FST gene promoter, consequently reducing cell proliferation and promoting a better understanding of hair follicle development mechanisms.
55 citations
,
June 2014 in “Nature Communications” This study found that overexpression of the transcription factor Tcf3 accelerates keratinocyte migration and skin wound healing in mice, highlighting its potential as a therapeutic target for wound repair.
November 2025 in “BMC Endocrine Disorders” This study found that in PCOS patients, a lower TT/DHT ratio is associated with regular menstruation, while higher ratios are linked to insulin resistance, suggesting its potential as a biomarker for metabolic severity in these patients.
9 citations
,
April 2013 in “Journal of Chromatography B” This study developed and validated a sensitive LC-MS/MS method for quantifying tamsulosin in human serum, achieving high analyte recovery and demonstrating applicability in clinical research for benign prostatic hyperplasia.
6 citations
,
November 1980 in “Clinical Endocrinology” This study measured plasma testosterone glucosiduronate levels and found no overlap in those with hyperandrogenism compared to normal females, despite normal testosterone and dihydrotestosterone levels in half of the affected patients.
506 citations
,
March 2005 in “The Journal of Clinical Endocrinology and Metabolism” This study found that testosterone therapy improved physical performance and strength in older men with low testosterone over 36 months, whether administered alone or with finasteride.
July 2024 in “Journal of Investigative Dermatology” Topical thyroid hormones may boost hair growth.
4 citations
,
July 2023 in “Frontiers in Microbiology” HGF combined with ADA is highly accurate for diagnosing tuberculous pleural effusion, especially in younger females.
20 citations
,
March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” This study found a direct correlation between the testicular feminization gene and decreased androgen receptor activity, potentially explaining the androgen insensitivity in affected individuals.
4 citations
,
September 1993 in “Steroids” This paper details a method for measuring testosterone metabolism into seven androgens using digital autoradiography, which offers high sensitivity and reduces the need for radioactive materials.
12 citations
,
December 2017 in “Scientific reports” This study reported that pulverizing hair samples significantly improves the precision of testosterone measurement, with higher testosterone concentrations observed in men than in women.
January 2022 in “International Journal of Medicine in Developing Countries” In this study, 35.4% of telogen effluvium patients showed ferritin deficiency and 34.2% had vitamin D deficiency, suggesting these should be included in TE screening; TSH testing should be individualized.
January 2024 in “İstanbul Kuzey Klinikleri” This study found that low ferritin levels are associated with higher telogen ratios in women with diffuse hair loss, suggesting an important role of ferritin in telogen effluvium diagnosis.
28 citations
,
November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study indicates that the normal human prostate is not a major contributor to circulating blood DHT concentrations in androgen-deficient patients receiving testosterone replacement therapy.
66 citations
,
October 1987 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that serum 3 alpha-diol G levels in women with idiopathic hirsutism correlated well with their clinical response to treatment, suggesting its usefulness in evaluating treatment outcomes.
This study suggests that topically applied thyroid hormones T3 and T4 promote hair growth on human scalp tissues ex vivo, highlighting potential therapeutic use for hair loss conditions like androgenetic alopecia.
32 citations
,
January 2000 in “International Journal of Cancer” In this study, the researchers observed significant down-regulation of Transglutaminase-3 expression in esophageal cancer tissues compared to normal tissues, suggesting its alteration is a common event in esophageal cancer development.
22 citations
,
May 2006 in “Experimental and Clinical Endocrinology & Diabetes” This study found that calculated parameters like free testosterone and bioavailable testosterone were higher in women with hirsutism and PCOS compared to controls, suggesting these might better assess hyperandrogenemia than measured hormone values.
9 citations
,
January 2017 in “Ginekologia Polska” This study found that the total testosterone/dihydrotestosterone ratio correlates with a negative metabolic profile in both women with PCOS and healthy women.
May 2022 in “Endocrine practice” This case report illustrates that high-dose biotin supplementation can cause false thyroid function test abnormalities in vitro, emphasizing the need to assess biotin intake before testing.
7 citations
,
March 2012 in “Journal of Investigative Dermatology” This study presents evidence that specific thymus-derived peptides affect human hair follicle growth, identifying thymulin as a potential hair growth stimulator despite interindividual response variations.
7 citations
,
April 1979 in “The Journal of Pediatrics” 1 citations
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January 2010 in “Endocrine abstracts”
This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets through its conversion to DHT and E2, a process disrupted by 5α-reductase and aromatase inhibitors.
This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets, requiring conversion to DHT and E2 via SRD5A1 and aromatase.
April 2019 in “Journal of the Endocrine Society” The researchers reported a case of falsely elevated testosterone in a teen, due to immunoassay interference, demonstrating that liquid chromatography tandem-mass spectrometry provides more accurate testosterone measurement, emphasizing the need for thorough analysis when clinical results are inconsistent.
November 2022 in “Journal of the Endocrine Society” This case study highlighted that excessive iodide intake from the supplement TauriNac was associated with the development of hypothyroidism in a cystic fibrosis patient, which reversed upon discontinuation.