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    Did you mean Follicular Differentiation?
    Glossary Follicular Differentiation

    process where hair follicle cells become specialized for hair growth

    Follicular differentiation is the process by which cells in the hair follicle develop into specialized types that contribute to hair growth. This involves the transformation of stem cells into various cell types, such as those forming the hair shaft, inner root sheath, and sebaceous glands, each playing a crucial role in the structure and function of the hair.

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    1. The upper dermal sheath has a potential to regenerate the hair in the rat follicular epidermis Differentiation · 1996 · 31 citations
    2. Follicular and epidermal alterations in patients treated with ZD1839 (Iressa), an inhibitor of the epidermal growth factor receptor 2002 · 169 citations
    3. Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets. PubMed · 2016 · 39 citations
    4. Faculty Opinions recommendation of The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2008
    5. The Progress of Epidermal Stem Cell Research 2010
    6. Epidermal hyperplasia and oral carcinoma in mice overexpressing the transcription factor ATF3 in basal epithelial cells Molecular Carcinogenesis · 2007 · 31 citations
    7. Cutaneous Side Effects in Non-Small Cell Lung Cancer Patients Treated with Iressa (ZD1839), an Inhibitor of Epidermal Growth Factor Acta Dermato Venereologica · 2003 · 116 citations
    8. Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells Annals of the New York Academy of Sciences · 1991 · 31 citations
    9. Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing Journal of Investigative Dermatology · 2008 · 99 citations
    10. Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins British Journal of Dermatology · 2006 · 63 citations
    11. 889 Trpv3 gain-of-function mutation impairs differentiation of hair follicle inner root sheath 2019
    12. Cystatin M/E Variant Causes Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans by Dysregulating Cathepsins L and V Frontiers in Genetics · 2021 · 6 citations
    13. The changes in the expression levels of follicular markers in keratoacanthoma depend on the stage: keratoacanthoma is a follicular neoplasm exhibiting infundibular/isthmic differentiation without expression of CK15 Journal of Cutaneous Pathology · 2014 · 28 citations
    14. Gate keeping the sebaceous gland bioRxiv (Cold Spring Harbor Laboratory) · 2023
    15. Impaired Notch‐MKP‐1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biology Experimental dermatology · 2013 · 112 citations
    16. Hair Growth Promoting Effect of Radish Crude Saponin Extract on Athymic Nude Mice The International Journal of Advanced Smart Convergence · 2019
    17. 1435 Enzymatic digestion of scalp hair follicle bulge allows to have more bulge-derived stem keratinocytes than explant isolation 2023
    18. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction Journal of Dermatological Science · 2017 · 35 citations
    19. Ultrastructural Localization and Quantification of Extracellular Calcium Binding Sites in Mouse Vibrissa and Human Scalp Follicles Skin Pharmacology and Physiology · 1993 · 1 citations
    20. Follicular ichthyosis 1984 · 17 citations
    21. Specific In Vivo Ablation of Lrig1-Positive Follicular Progenitor Cells Results in Sebaceous Gland Loss in Mice International Journal of Molecular Sciences · 2026
    22. Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors. PubMed · 2008 · 35 citations
    23. Mode of action of mouse epidermal growth factor on the wool follicles of Merino sheep: an ultrastructural study Australian Journal of Agricultural Research · 1989 · 9 citations
    24. Hair Follicle Stem Cell SLC3A2 Regulates Epithelial Regenerative Properties Journal of Investigative Dermatology · 2025
    25. [Development of interfollicular epidermis on the surface of collagen framework of the dermis in experimental animals]. PubMed · 1992
    26. Follicular induction and CK20+ Merkel cells overlying cutaneous focal mucinosis Journal of cutaneous pathology · 2018 · 1 citations
    27. Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia Cell death and differentiation · 2012 · 19 citations
    28. Activated Kras Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling Journal of Investigative Dermatology · 2010 · 29 citations
    29. A case of localized follicular hamartoma: an ultrastructural and immunohistochemical study Journal of Cutaneous Pathology · 2000 · 21 citations
    30. 874 Chromatin architectural protein CTCF controls epidermal barrier formation, hair follicle fate maintenance and suppresses inflammatory responses in the skin epithelium Journal of Investigative Dermatology · 2017