1 citations
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December 2012 in “Journal of dermatological science” This study introduces ficlatuzumab, an anti-HGF monoclonal antibody, in combination with gefitinib in a phase 2 trial to address EGFR TKI resistance in Asian NSCLC patients.
15 citations
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July 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that fluorescence excitation spectroscopy could be a promising noninvasive tool for assessing the effects of comedolytic agents like retinoids on acne-like lesions in rhino mice.
177 citations
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December 2002 in “The Lancet” In this study, single fibrinogen/LDL apheresis showed a significant improvement in speech perception for patients with plasma fibrinogen concentrations over 295 mg/dL compared to standard treatment for sudden sensorineural hearing loss.
3 citations
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February 2019 in “Animal biotechnology” In this study, the PLP2 gene was found to promote secondary hair follicle development in Liaoning cashmere goats, with its expression negatively regulated by melatonin and potentially affecting follicle development via the BMP pathway.
April 2018 in “Plastic & Reconstructive Surgery Global Open” This study successfully isolated LGR6+ epithelial stem cells from rats and demonstrated their multipotency, suggesting potential for fracture healing research.
35 citations
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May 2019 in “Frontiers in genetics” This study reported that specific non-coding RNAs may regulate the hair follicle cycle in Angora rabbits by acting as competitive endogenous RNAs, enhancing understanding of ncRNA roles in hair growth.
January 2025 in “BMC Genomics” This study examined the role of long non-coding RNAs in wool fineness among Gansu alpine fine-wool sheep, identifying specific lncRNAs and target genes that may enhance wool quality.
March 2026 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” In this study, L-PRF was associated with successful osseointegration and tissue healing when used with biomaterial for dental implants in a patient with an atretic bone ridge.
May 2014 in “Clinical and Experimental Dermatology” A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.
January 2018 in “International Educational Applied Scientific Research Journal” This study observed an increase in hair thickness and reduced hair loss in patients with androgenetic alopecia after treatment with autologous cellular suspension using the Rigenera® system, though further research is needed.
14 citations
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June 2021 in “British journal of dermatology/British journal of dermatology, Supplement” This paper presents consensus guidelines for standardized diagnostic criteria and assessment methods for frontal fibrosing alopecia to improve clinical research and data collection globally.
April 2023 in “Journal of Investigative Dermatology” This study found that overexpression of the lncRNA AL136131.3 may inhibit hair shaft growth and promote hair follicle apoptosis in androgenetic alopecia by influencing key metabolic pathways.
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers developed a new method called Enriched-GF, which enhances growth factor recovery from platelet concentrates through a combination of glass bead activation, freeze-thaw cycling, and calcium stimulation, outperforming conventional methods by providing higher and more consistent yields for regenerative medicine applications.
September 2022 in “British Dental Journal” Platelet-rich fibrin is becoming popular for medical and cosmetic uses like hair growth and natural fillers.
In this study, researchers analyzed over 5,000 T cells per sample using scRNA+TCR-seq technology and found that dual TCR Tregs are present in high proportions across various mouse tissues, showing unique TCR pairing patterns, V(D)J usage, and mRNA expression compared to single TCR Tregs.
Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.
8 citations
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July 2020 in “Clinical, cosmetic and investigational dermatology” This review hypothesizes that excessive facial photo-protection may contribute to frontal fibrosing alopecia by disrupting immunological homeostasis through the aryl hydrocarbon receptor-kynurenine pathway, but it reports no new clinical results.
18 citations
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February 2018 in “Journal of the American Academy of Dermatology” This study reports no new clinical results but suggests a potential relationship between frontal fibrosing alopecia and cutaneous conditions such as rosacea, indicating a need for further research.
2 citations
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June 2021 in “Sultan Qaboos University medical journal” This case report presents three sisters with familial frontal fibrosing alopecia, making it the 25th documented familial case, with treatment results observed in one sister.
4 citations
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January 2021 in “International Journal of Medical Sciences” This study suggests that miR-182 may play an essential role in hallux valgus development by regulating FGF9 expression, indicating a potential therapeutic target for its treatment.
4 citations
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April 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review highlights available treatments for frontal fibrosing alopecia, noting that 5-alpha reductase inhibitors, intralesional steroids, and hydroxychloroquine currently have the most evidence supporting their use, while other treatments show variable results and require further study.
1 citations
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May 2023 in “PubMed” The researchers in this study identified a new subpopulation of dermal fibroblasts in neonatal murine dermis marked by EGFR, which they report contributes to hair follicle regeneration through the promotion of IGF1, potentially aiding in wound-induced hair follicle neogenesis.
June 2026 in “Journal of Cosmetic Dermatology” CGF-PF may improve hair loss treatment by targeting hair follicle stem cells more effectively.
July 2020 in “Journal of Tissue Engineering and Reconstructive Surgery”
February 2021 in “Dermatological reviews” In this study, a specially adapted nonablative radiofrequency device significantly increased hair growth measures in most patients with androgenetic alopecia, including hair count and density.
2 citations
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April 2017 in “Actas Dermo-Sifiliográficas” This review discusses the etiology, pathogenesis, clinical presentation, and treatment of frontal fibrosing alopecia, noting the lack of clinical trial data and limited observational treatment results.
1 citations
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December 2019 in “Protetyka Stomatologiczna” This review discusses the use of platelet-rich fibrin in medical fields, especially dentistry, and reports no new clinical results.
October 2025 in “Journal of the Endocrine Society” In this case report, a 21-year-old female with familial partial lipodystrophy type 2 and hyperandrogenism was found to have a rare Sertoli cell tumor of the ovary, highlighting an unusual presentation where links between these two rare conditions are still unknown.
166 citations
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April 2012 in “Journal of The American Academy of Dermatology” This study reviewed clinical data from 60 patients with frontal fibrosing alopecia and found increasing prevalence and generally poor response to treatment, with the cause remaining unclear.
February 2025 in “Journal of Clinical Investigation” This study found that RNase L acts as a regeneration repressor gene in mammals, as seen in Rnasel-/- mice which showed increased regenerative capacity and elevated Wound Induced Hair Neogenesis through enhanced IL-36α signaling, suggesting a tradeoff between regeneration and immune regulation.