Platelet-Rich Fibrin: New Course in Regenerative Medicine and Dentistry

    December 2019 in “ Protetyka Stomatologiczna ”
    Monika Tysiąc-Miśta, Sylwia Bulanda, Olaf Gruca, Magdalena Wyszyńska, Jacek Kasperski
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    TLDR Platelet-Rich Fibrin shows promise in medicine and dentistry, but more research is needed to standardize its use.
    The document from December 4, 2019, discussed Platelet-Rich Fibrin (PRF), a fibrin matrix derived from a patient's blood, and its applications in various medical fields, particularly dentistry and aesthetic medicine. PRF was used in oral surgery, periodontics, endodontics, implantology, pediatric dentistry, orthopedics, skin regeneration, acne treatment, scar and wrinkle removal, and androgenetic alopecia therapy. The document highlighted that the clinical efficacy of PRF was highly debatable due to limited evidence-based clinical literature and poor understanding of PRF biocomponents. Despite this, PRF gained a growing number of supporters and its application continued to expand. Modifications to the preparation protocol led to preparations with better effects (L-PRF, A-PRF, S-PRF). However, the document concluded that randomized studies on a large research group were still insufficient for standardizing the method of preparation depending on the application.
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