Non-Transfusional Hemocomponents: From Biology to the Clinic—A Literature Review

    March 2018 in “ Bioengineering ”
    Roberta Gasparro, Erda Qorri, Alessandra Valletta, Michele Masucci, Pasquale Sammartino, Alessandra Amato, Gaetano Marenzi
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    TLDR The document concludes that products like PRP and PRF show promise for tissue healing, but evidence of their effectiveness is inconsistent.
    The document reviewed the applications of autologous products like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in promoting tissue regeneration, hemostasis, and wound healing in various medical fields. It covered the history, classification, and biological behavior of these hemocomponents, as well as their clinical applications in reconstructive surgery, periodontology, sports medicine, and dermatology. Despite the potential benefits, the review noted inconsistent and inconclusive evidence regarding their effectiveness. It also mentioned ongoing research aimed at enhancing the therapeutic effects of PRP and PRF in regenerative medicine.
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