TLDR The document concludes that products like PRP and PRF show promise for tissue healing, but evidence of their effectiveness is inconsistent.
The document reviewed the applications of autologous products like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in promoting tissue regeneration, hemostasis, and wound healing in various medical fields. It covered the history, classification, and biological behavior of these hemocomponents, as well as their clinical applications in reconstructive surgery, periodontology, sports medicine, and dermatology. Despite the potential benefits, the review noted inconsistent and inconclusive evidence regarding their effectiveness. It also mentioned ongoing research aimed at enhancing the therapeutic effects of PRP and PRF in regenerative medicine.
136 citations,
April 2016 in “Dermatologic Surgery” PRP treatment helps hair growth and density in androgenetic alopecia patients.
214 citations,
September 2015 in “Stem Cells Translational Medicine” Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
113 citations,
July 2015 in “Journal of Cosmetic Dermatology” Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.
May 2022 in “Acta scientific dental sciences” Platelet concentrates are useful for tissue repair in medicine and dentistry, with L-PRF showing promising results in various treatments.
April 2024 in “Military Medical Research/Military medical research” Cellular and immunotherapies show promise for healing chronic wounds but need more research.
July 2024 in “Periodontology 2000” Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.
August 2021 in “International Journal of Dermatology and Venereology” Platelet-Rich Fibrin (PRF) can speed up healing in chronic wounds, improve hair density, and act as a natural filler for skin rejuvenation, but its use in hair loss treatment needs more evaluation.
January 2023 in “Annali di stomatologia” PRP helps heal and repair tissues in medicine but needs more research for better use.
14 citations,
July 2021 in “Biomedicines” Platelet-rich treatments can help improve wound healing and tissue repair.