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research Challenging 100% Purity: Unveiling Aloe Vera's Optimal Role in Hair Restoration with Injectable Platelet-Rich Fibrin

January 2025 in “Annals of dental specialty”

This study found that Aloe Vera, injectable platelet-rich fibrin (i-PRF), and their combination affected the proliferation of mesenchymal stem cells derived from human hair follicles, with varying concentrations tested for proliferation and cytotoxic effects.

research Platelet-Rich Fibrin – new course in regenerative medicine and dentistry

1 citations , December 2019 in “Protetyka Stomatologiczna”

This review discusses the use of platelet-rich fibrin in medical fields, especially dentistry, and reports no new clinical results.

research An In vitro Study Comparing the Survival of Hair Follicles in Various Storage Media at Different Temperatures for Hair Transplant Procedure

March 2025 in “International Journal of Trichology”

In this study, researchers found that storing hair grafts at 37°C with 10% DMEM led to better graft survival compared to other solutions and temperatures, suggesting this method may enhance graft longevity and therapeutic outcomes.

research Role of Platelet Rich Fibrin (PRF) in Treatment of Post Acne Scars: Review Article

April 2022 in “The Egyptian Journal of Hospital Medicine”

This review examines the use of platelet rich fibrin for treating post-acne scars and reports no new clinical results; it highlights that fibrin's matrix enables a prolonged release of growth factors.

research PLATELET RICH FIBRIN- A Natural Regenerative Biomaterial

October 2023 in “Journal of Advanced Sciences”

This review highlights PRF's potential as a regenerative medicine tool, detailing its diverse applications in dentistry, orthopedics, and dermatology, but presents no new clinical results.

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Clinics

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Community Join

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community Just got my first I-PRF Injection...

4 upvotes 4 years ago

A user shared their experience with hair loss treatments, including I-PRF injections, mesotherapy, and a topical solution containing Minoxidil and Finasteride. After experiencing side effects, they decided to stop the medicinal treatments and focus on natural alternatives like I-PRF, microneedling, and essential oils.

community I'm having good initial results from PRF after an illness--ask me anything

2 upvotes 1 year ago

The user experienced hair loss after chikungunya and started PRF (platelet-rich fibrin) injections with injectable Dutasteride, noticing new hair growth. They are hopeful for continued improvement.

community What is everyone's stack and why?

21 upvotes 1 year ago

People are using various treatments for hair loss, including dutasteride, finasteride, minoxidil (both oral and topical), RU58841, and ketoconazole shampoo. Some also use additional methods like microneedling, vitamins, and oils, with mixed results and personal preferences influencing their choices.

community Thoughts on Bryan Johnson’s new hair loss product?

143 upvotes 1 year ago

Bryan Johnson's new hair loss product, which includes peptides, is viewed skeptically by many, with concerns it may be a money grab rather than an effective treatment. Most users prefer proven treatments like finasteride and minoxidil, which are cheaper and have established results.

community When Life Starts Taking Your Hair... And Then Your Confidence: A 25-Year-Old’s Battle with Hair Loss

in Chat 124 upvotes 1 year ago

A 25-year-old discusses hair loss and its impact on confidence, considering treatments like finasteride and minoxidil. Recommendations include these medications and lifestyle changes to manage hair loss.

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Learn

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learn Botox

What’s the science behind Botox injections for androgenetic alopecia? Small published studies and a 2025 meta-analysis report hair-count gains from scalp botulinum toxin injections, but nearly all of them lack control groups, and reviewers of the same literature call the evidence low-quality; the treatment is off-label and not approved for hair loss anywhere.

learn Glycerin

What’s the difference between vegetable glycerin and synthetic glycerin in hair products? Vegetable glycerin is plant-derived, while synthetic glycerin is petroleum-based, but both are chemically identical.

learn Hyaluronic Acid

What’s the difference between using hyaluronic acid as a serum on the scalp versus taking it as a supplement? A serum sits on the scalp surface. Oral hyaluronic acid has small trials on facial wrinkles, none on the scalp or hair.

learn Salicylic acid

What’s the difference between using salicylic acid for scalp exfoliation versus regular shampooing? Salicylic acid loosens dead skin cells in the scalp's outer layer, while regular shampoo mainly washes away surface oil and dirt.

learn Pyrithione Zinc

What’s the difference between pyrithione zinc and salicylic acid when treating scalp buildup? Pyrithione zinc is an antifungal that slows the yeast linked to dandruff, while salicylic acid loosens and sheds scale; both are permitted US over-the-counter dandruff ingredients. Zinc pyrithione has been banned in EU cosmetics since 2022 because it is classified as toxic for reproduction.

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