Role of Platelet-Rich Fibrin in the Treatment of Post-Acne Scars: Review Article
April 2022
in “
The Egyptian Journal of Hospital Medicine
”
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Studysummary This review examines the use of platelet rich fibrin for treating post-acne scars and reports no new clinical results; it highlights that fibrin's matrix enables a prolonged release of growth factors. Our plain-language summary of this paper — not a Tressless recommendation.
The article "Role of Platelet Rich Fibrin (PRF) in Treatment of Post Acne Scars" reviews the potential use of PRF in treating acne scars. Acne scars, which negatively impact personal and professional relationships, are primarily caused by abnormal collagen creation or breakdown during healing. The majority of these scars are atrophic, resulting from collagen degradation at the dermal level. PRF was introduced into acne scar treatment after platelet-derived growth factor (PDGF) was found to stimulate wound healing, angiogenesis, and tissue remodeling. The study concludes that cell migration and proliferation are more efficient when fibrin is rich in platelets. Compared to platelet-rich plasma, the fibrin matrix allows for a slow and steady release of growth factors over time.
