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Targeting thyroid hormone receptor α in liver cells may help treat liver fibrosis.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

Cannabinoids might help treat skin problems but more research is needed to be sure.

Metformin might help treat certain skin conditions, but more research is needed.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Cannabinoids may help treat various skin conditions.

Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.

Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

The technique effectively shows how human skin and hair cells form into ball-like structures.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Mice can regrow hair on wounds due to specific cell interactions and mechanical forces not seen in rats.

The study found that p63 needs signals from morphogens to help skin cells differentiate properly.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Different types of skin cells play specific roles in development, healing, and cancer.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.