31 citations,
January 2014 in “Clinical Endocrinology” The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.
21 citations,
September 2017 in “Journal of Obstetrics and Gynaecology Research” Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.
12 citations,
May 2005 in “Fertility and Sterility” Higher insulin levels are linked to larger ovaries in women with idiopathic hirsutism.
1 citations,
June 2019 in “Innovare journal of medical sciences” Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.
1 citations,
June 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.
May 2023 in “Journal of Cosmetic Dermatology” Being overweight can cause or worsen skin problems in children, some more common in darker skin, and is often linked to insulin resistance.
June 2021 in “International Journal of Research in Dermatology” Women with acne and PCOS should be checked for insulin resistance and related symptoms.
May 2020 in “Fertility and Sterility” Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.
March 2019 in “Evidence Based Women Health Journal (Online)” Vitamin D supplements increased ovulation rates in women with PCOS who were vitamin D deficient.
September 2008 in “Fertility and Sterility” Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.
February 2020 in “Benha Journal of Applied Sciences” Higher Galectin-3 levels are linked to insulin resistance and may predict androgenetic alopecia severity.
January 2017 in “IP Indian journal of clinical and experimental dermatology” Early-onset male baldness is not linked to insulin resistance, but is significantly associated with metabolic syndrome.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
249 citations,
November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
200 citations,
August 2009 in “Experimental dermatology” Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
56 citations,
July 2008 in “European journal of endocrinology” Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.
44 citations,
May 2008 in “Fertility and Sterility” Insulin resistance might not be enough to worsen blood vessel function in young, nonobese women with polycystic ovary syndrome.
40 citations,
April 2008 in “European journal of endocrinology” Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
36 citations,
October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
34 citations,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.
30 citations,
September 2017 in “Clinics in Dermatology” Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.
18 citations,
December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
18 citations,
February 2010 in “Odontology” The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.
14 citations,
September 2017 in “Clinics in Dermatology” Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.
11 citations,
January 2017 in “Journal of Endocrinology/Journal of endocrinology” Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
10 citations,
September 2015 in “Gynecological Endocrinology” Both treatments reduced excessive hair growth in PCOS, but there was no difference in weight, hair score, hormone levels, or insulin resistance.
4 citations,
February 2019 in “Biological Trace Element Research” Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.
2 citations,
January 2023 in “Research Square (Research Square)” Managing emotional distress, obesity, insulin resistance, and high male hormones is crucial for improving well-being in women with PCOS.
2 citations,
January 2019 in “Egyptian Journal of Dermatology and Venereology” Insulin might be involved in causing hair loss and acne.
1 citations,
November 2023 in “Reproductive biology and endocrinology” Most women with PCOS have insulin resistance, especially those with phenotype B.