Left Ventricular Myocardial Mass Index and Its Correlates as an Early Marker of Cardiovascular Risk Among Nonobese Normotensive Indian Women With Polycystic Ovary Syndrome: Lessons From a Cross-Sectional Study

    May 2020 in “ Fertility and Sterility ”
    Aafia Rashid, Muhammad Akbar, Idrees Ahmed Wani, Imran Hafeez, Tabasum Parvez, Mohd Afzal Zagar, Mohd Ashraf Ganie
    Image of study
    TLDR Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.
    In a cross-sectional study from June 2020 involving 260 nonobese, normotensive Indian women with polycystic ovary syndrome (PCOS) and 250 healthy controls, it was found that the PCOS group had a significantly higher left ventricular myocardial mass index (LVMI) than the control group. The study also revealed that women with PCOS had higher levels of insulin resistance (IR) and inflammatory markers, which were positively correlated with LVMI, but not with hyperandrogenism. These findings suggest that nonobese, normotensive women with PCOS may have an increased risk of cardiovascular issues, associated more with inflammation and IR than with androgen excess. The authors recommend further long-term studies with larger cohorts to better assess cardiovascular risk in this population.
    Discuss this study in the Community →

    Research cited in this study

    7 / 7 results

    Related Community Posts Join

    6 / 12 results

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  56 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 2 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community C’est terrible - at my wits end

      in Female  443 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Why balding gets worse in every generation?

      in Chat  81 upvotes 5 months ago
      Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

    Similar Research

    5 / 1000+ results