The Association of Metabolic Syndrome and Insulin Resistance in Early-Onset Androgenetic Alopecia in Males: A Case-Control Study

    January 2017 in “ IP Indian journal of clinical and experimental dermatology ”
    Mukunda Ranga Swaroop, Manohara Bk, BD Sathyanarayana, Dakhane Yogesh, Jigalikoppa Raghavendra
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    TLDR Early-onset male baldness is not linked to insulin resistance, but is significantly associated with metabolic syndrome.
    The study conducted in 2016 involved 50 male patients with early-onset Androgenetic alopecia (AGA) and 50 control subjects. The majority of the patients with early-onset AGA were in the age group of 22-24 years, and the most common grade of hair loss was grade III a (32%) according to the Hamilton-Norwood scale of hair loss. The study found that 10% of the cases and 4% of the controls showed an association with insulin resistance, but this difference was not statistically significant (p= 0.23). However, 30% of the cases and 8% of the controls showed an association with metabolic syndrome, and this difference was statistically significant (p= 0.005). The study concluded that male patients with early-onset AGA were not associated with insulin resistance, but metabolic syndrome was associated with these patients.
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