The Association of Metabolic Syndrome and Insulin Resistance in Early-Onset Androgenetic Alopecia in Males: A Case-Control Study

    January 2017 in “ IP Indian journal of clinical and experimental dermatology ”
    Mukunda Ranga Swaroop, Manohara Bk, BD Sathyanarayana, Dakhane Yogesh, Jigalikoppa Raghavendra
    Image of study
    TLDR Early-onset male baldness is not linked to insulin resistance, but is significantly associated with metabolic syndrome.
    The study conducted in 2016 involved 50 male patients with early-onset Androgenetic alopecia (AGA) and 50 control subjects. The majority of the patients with early-onset AGA were in the age group of 22-24 years, and the most common grade of hair loss was grade III a (32%) according to the Hamilton-Norwood scale of hair loss. The study found that 10% of the cases and 4% of the controls showed an association with insulin resistance, but this difference was not statistically significant (p= 0.23). However, 30% of the cases and 8% of the controls showed an association with metabolic syndrome, and this difference was statistically significant (p= 0.005). The study concluded that male patients with early-onset AGA were not associated with insulin resistance, but metabolic syndrome was associated with these patients.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Having androgen receptor density and sensitivity at wrong f*ing place

      in Satire  7 upvotes 2 months ago
      The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 3 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community Follicum releases some data from previous phase 2a trial

      in Research/Science  13 upvotes 1 year ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  142 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

    Related Research

    9 / 9 results