TLDR Higher Galectin-3 levels are linked to insulin resistance and may predict androgenetic alopecia severity.
This study investigated the relationship between serum Galectin-3 levels and insulin resistance in patients with androgenetic alopecia (AGA). Conducted on 60 AGA patients and 20 healthy controls, the research found that higher levels of Galectin-3 and HOMA-IR were independent predictors of AGA development and severity in both males and females. The study used enzyme-linked immunosorbent assay (ELISA) to measure serum levels, with Galectin-3 showing an AUC of 0.978 and HOMA-IR an AUC of 0.967, both with 93.3% sensitivity and specificity at their respective cut-off values. These findings suggested that Galectin-3 could be a potential therapeutic target for restoring insulin sensitivity in AGA patients.
38 citations,
November 2013 in “Journal of The American Academy of Dermatology” Higher BMI links to worse hair loss in Taiwanese men.
110 citations,
July 2010 in “Journal of The American Academy of Dermatology” Hair loss linked to higher heart disease risk in both men and women.
69 citations,
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66 citations,
February 2009 in “British Journal of Dermatology” Chinese men have lower AGA rates than Caucasians, with type III vertex most common; family history is important.
157 citations,
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115 citations,
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32 citations,
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Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.
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13 citations,
January 2019 in “Indian Journal of Dermatology” Men with early-onset hair loss have more heart disease risk factors.
138 citations,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
