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This study found that paeonol-loaded liposomal gels demonstrated antioxidant effects and relieved inflammation in AD-like mice, suggesting potential benefits for treating atopic dermatitis.

This review highlights the potential of valorizing vegetable waste by extracting valuable biomolecules for use in food, nutraceuticals, and energy, noting that while promising methods exist, several niche areas lack sufficient research on a global scale.

PEVs effectively deliver minoxidil through skin.

In this study, FOL-026, a peptide based on osteopontin, was shown to promote angiogenesis and stimulate vascular cell proliferation and migration through neuropilin-1, similar to VEGF, suggesting potential therapeutic applications in vascular repair and angiogenesis-related conditions.

This study found that penetration enhancer-containing vesicles significantly improved minoxidil delivery to the skin compared to traditional liposomes and penetration enhancer-containing ethanolic solutions, with deformability linked to enhanced deposition.

VIP reduces hair pigmentation by decreasing melanin production.

This study found that the evodiamine derivative 2-16 exhibited the highest antitumor activity and a broad spectrum of activity against various human cancer cell lines, with improved solubility.

This study found that an extract from the herbal medicine Ophioglossum vulgatum Linn. showed potential hair growth promotion and increased ATP and catalase activity in cell assays, suggesting its use in treating alopecia.

This study presented at the ASCO Annual Meeting reported that the epidermal growth factor receptor antibody ABX-EGF showed preliminary efficacy in renal cell cancer patients, with tolerable side effects, while bortezomib demonstrated clinical benefit in a significant proportion of multiple myeloma patients.

This review summarizes recent advances in the development of engineered polypeptide-based drug delivery systems for cancer therapy, highlighting their potential to improve treatment efficacy and reduce side effects.

This study of HCPS survivors in Chile found that 61.9% reported incomplete recovery at 3-6 months post-symptom onset, with ECMO users experiencing more motor dysfunction and palpitations, highlighting the need for multidisciplinary care to address persistent symptoms.

This study observed that plant-derived extracellular vesicles delivered through a microneedling technique showed favorable tolerance and subjective improvement in androgenetic alopecia patients, with 95% reporting perceived improvement and 85% experiencing no adverse effects after six sessions.

In this study, the researchers report that a modified epimorphin-derived peptide shows potential for hair follicle regeneration, especially when used with 1% minoxidil in mice.

This study found no clinically significant effects of intraovarian injection of platelet-rich plasma on ovarian function over one year in patients with extremely low functional ovarian reserve.

This study found that valproic acid-loaded microemulsion formulations enhanced skin penetration pathways in guinea pigs compared to an aqueous solution, with composition elements like oil content and surfactant ratios significantly affecting drug delivery performance.

This study demonstrated that EVs from pluripotent stem cell-derived mesenchymal stem cells improved recovery and function in ischemic lower limbs by enhancing angiogenesis through the ERK/MAPK signaling pathway.

In this study conducted on mouse fetuses, valproic acid was found to reduce Sonic Hedgehog expression in the skin and hair follicles, but the inclusion of vitamin E helped mitigate this effect, supporting its potential role in managing valproic acid-induced changes.

This study found that P. cornucopiae extract showed antioxidant and protective effects on human skin fibroblasts, suggesting its potential as an antiaging agent by preventing oxidative stress-induced collagen breakdown.

BOOST is a promising, easy-to-use treatment for diabetic foot ulcers that improves healing by reducing inflammation and promoting blood vessel growth.

This review analyzed 12 clinical studies on extracellular vesicle therapies, finding potential benefits for skin aging, acne scars, alopecia, and wound healing, but highlighted significant challenges like production standardization and lack of large-scale studies.

This report discusses two cases of porokeratotic eccrine ostial and dermal duct nevus and porokeratotic eccrine and hair follicle nevus, suggesting they may represent a single clinical entity, but reports no therapeutic outcomes.

This study found that the combination of recombinant growth factors and plant-derived extracellular vesicles significantly improved scalp regulation, hair growth, thickness, and density, and reduced hair shedding in the tested formulation by Day 56.

This study developed an algorithm for predicting the impact of innovations on economic growth and reported its potential to enhance innovation policy decisions.

This study introduced a viscoelastic dry electrode that successfully reduces motion artifacts in EP monitoring on hairy skin, maintaining stable performance for up to 48 days.

This review discusses the capabilities of ethosomes as drug delivery carriers and reports improved outcomes in a clinical study with an ethosomal acyclovir formulation.

This study used human stem cell-derived skin organoids to model EV-A71 infection, revealing that various skin cell types are susceptible to the virus and identifying a potential drug target and replication inhibitor, suggesting its utility for studying skin infectious diseases and drug screening.

In this study, intradermal injections of extracellular vesicles over six months were reported to be safe and effective in improving hair growth among patients with pattern hair loss, with favorable response linked to specific patient factors and treatment volumes.

This study developed a stable nanoemulsion of Avicennia marina heartwood extract showing promising anti-dandruff activity against Pityrosporum ovale and favorable physicochemical properties, which supports its potential use in topical formulations.

This review discusses the potential of extracellular vesicles from various sources for skin rejuvenation and cosmetic use, noting promising results, especially with mesenchymal stem cell-derived vesicles, but reports no new clinical results.

This study found that arginine vasotocin is evolutionarily conserved across diverse taxa and may play roles in neuroendocrine, immune, and stress signaling, with potential antimicrobial applications.