An Off-The-Shelf Bioactive EV Delivering Cryogel Orchestrating Immunomodulatory Reprogramming and Angiogenesis for Diabetic Ulcer Healing

    February 2026 in “ Biomaterials ”
    Parvaiz Ahmad Shiekh, Ubaid Tariq, Durga Nandini Athmuri … Prajesh Nayak
    Studysummary BOOST is a promising, easy-to-use treatment for diabetic foot ulcers that improves healing by reducing inflammation and promoting blood vessel growth.
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    Research cited in this study 8

    1. Platelet Extracellular Vesicles Loaded Gelatine Hydrogels for Wound Care Advanced Healthcare Materials · 2024
    2. Type III Collagen Regulates Matrix Architecture and Mechanosensing During Wound Healing Journal of Investigative Dermatology · 2024
    3. Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Cutaneous Wound Healing in Type 2 Diabetic Mice via Macrophage Pyroptosis Inhibition Stem cell research & therapy · 2023
    4. Extracellular Vesicles in Skin Wound Healing Pharmaceuticals · 2021
    5. Human Acellular Amniotic Membrane Incorporating Exosomes from Adipose-Derived Mesenchymal Stem Cells Promotes Diabetic Wound Healing Stem Cell Research & Therapy · 2021
    6. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    7. Scarless Wound Healing: Finding the Right Cells and Signals Cell and Tissue Research · 2016
    8. New Hair From Healing Wounds Nature · 2007