Porokeratotic Eccrine Ostial And Dermal Duct Nevus And Porokeratotic Eccrine And Hair Follicle Nevus: Is Nomenclature 'Porokeratotic Adnexal Ostial Nevus' More Appropriate?
January 2019
in “
Indian Dermatology Online Journal
”
Porokeratotic Eccrine Ostial and Dermal Duct Nevus PEODDN Porokeratotic Eccrine and Hair Follicle Nevus PEHFN Porokeratotic Adnexal Ostial Nevus PAON adnexal hamartomas hyperkeratosis acanthosis cornoid lamella eccrine acrosyringia hair follicle ostia porokeratotic nevus adnexal nevus skin lesions skin growths
TLDR The term "Porokeratotic Adnexal Ostial Nevus" is suggested as a more appropriate name.
The document discussed two cases of rare adnexal hamartomas: porokeratotic eccrine ostial and dermal duct nevus (PEODDN) and porokeratotic eccrine and hair follicle nevus (PEHFN). Both cases involved asymptomatic papular lesions present since birth or early childhood, with characteristic histological features. The study suggested that PEODDN and PEHFN might represent a single entity affecting different adnexal structures, proposing the term "porokeratotic adnexal ostial nevus" (PAON) as a more appropriate nomenclature. The pathogenesis was linked to mutations in the GJB2 gene encoding connexin 26. Various treatments have been used with variable success, reflecting the challenges in managing these conditions.
