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This study found that in Hutchinson–Gilford progeria syndrome, iPSCs committed to the keratinocyte lineage faster than normal cells, with LEF1 expression reduced and a partial rescue of the phenotype achieved through adenine base editing.

This study demonstrated that gene-corrected 3D skin constructs from RDEB patient-derived iPSCs, grafted onto immunocompetent mice, showed normal collagen VII expression after two months.

In this study, researchers propose that different vertebrate skin appendages, such as hair, feathers, and scales, evolved in parallel from a shared ancestral cell structure associated with teeth, dating back approximately 420 million years ago.

Two studies in Cell Stem Cell reported that human and mouse somatic cells can be reprogrammed into induced pluripotent stem cells using microRNAs, eliminating the need for ectopic protein expression.

A single medium, PRIME AIRLIFT, supports better human hair follicle formation in grafts.

This case report describes the occurrence of eruptive vellus hair cysts in twin patients, adding to the literature on this dermatological condition.

This study found that both allogeneic and xenogeneic small extracellular vesicles from adipose tissue similarly enhanced soft tissue regeneration and wound healing in rat models, implying similar therapeutic effects across species.

In a mouse model of infected burns, this study found that treatment with recombinant fusion peptide EK significantly decreased Pseudomonas aeruginosa colony count and improved wound healing rates compared to controls.

This paper discusses the recent advancements and challenges of flexible bioelectronics in personalized health management and cancer therapy, but reports no new studies or results.

Poly(ethylene-co-vinyl alcohol) monoliths can be made using heat separation for various uses.

In this study, researchers developed ScalpViT, a novel deep learning model, to improve the automated diagnosis of visually similar scalp diseases, achieving 94.3% accuracy and outperforming existing models like ResNet-50 and EfficientNet-B3 when tested on a diverse dataset of 7,000 images.

This study reports that mesenchymal stromal cell-derived extracellular vesicle injections led to complete hair regrowth in a patient with persistent chemotherapy-induced alopecia.

This case study highlights a pediatric instance of eruptive vellus hair cysts partially responding to calcipotriene cream, aiming to remind clinicians about this often overlooked condition.

This source describes the proceedings of the 7th International Conference on Evolutionary Medicine, summarizing over 100 scientific presentations focused on human development, health, and adaptation in changing environments, and commemorating Vilnius University's historical contributions to auxology and evolutionary medicine.

This study successfully established a functionally stable immortalized sheep granulosa cell line (GCs-SV40T-GFP) that can passaged up to 50 generations, maintaining morphological stability and estradiol secretion, offering a valuable model for research into animal reproductive function and hormone regulation.

This study reveals that epidermal stem cell differentiation in mice involves dynamic transcriptional changes, with Keratin-10 transcription preceding gradual chromatin compaction shifts associated with differentiation.

This study suggests that enhancing endocannabinoid tone with an EMT-inhibitor may have anti-inflammatory effects and slightly increase sebaceous lipid production, which could be beneficial for dry skin conditions.

This study found that transgenic mice with expression of HPV16 E6/E7 oncogenes showed improved ear tissue regeneration, including hair follicles and cartilage, without tumor formation.

This review highlights REV7's crucial roles in maintaining genome stability, its implication in several cancers, and its association with poor prognoses and treatment resistance, while also noting that REV7 suppression may improve chemotherapy sensitivity.

This study reports that improvements to the EczemaNet pipeline, incorporating pixel-level segmentation and data augmentation, enhanced the reliability and interpretability of assessing atopic dermatitis severity from digital images.

This study developed a rapid and efficient in vitro method using high-performance liquid chromatography to screen for steroid 5 alpha-reductase inhibitors, determining inhibition constants for Finasteride and Epristeride.

This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.

In this study, transient transfection of the HIF-1α gene into fibroblasts led to increased VEGF expression, which may enhance the growth and anagen phase of human hair follicles in vitro.

In this study, researchers identified a causal link between Epstein-Barr virus infection and clear cell renal cell carcinoma, highlighting GBP1 as a key target and suggesting finasteride as a potential inhibitor, offering a new direction for treatment strategies.

This study found that rat hair follicle stem cells can be effectively transfected with VEGF 165 using lentivirus vectors, suggesting their potential use in developing tissue-engineered skin with improved vascularization.

At the 21st Royan International Stem Cell Congress, researchers highlighted the growing integration in regenerative medicine, emphasizing advances in pluripotency, AI applications, and bioengineering for the development of accessible stem cell therapies.

This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.

In this study, the presence of the HPV11-E2 protein in transgenic mice was found to increase and vary the expression of a reporter gene in hair follicle bulge regions.

This review highlights how the development of forensic DNA phenotyping systems like IrisPlex, HIrisPlex, and HIrisPlex-S has advanced criminal investigation by accurately predicting physical traits such as eye, hair, and skin color from DNA, thereby improving the precision and relevance of forensic applications.

This study suggests that vitamin D-upregulated protein 1 (VDUP1) might play a unique role in regulating the differentiation of epidermal cells.