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180-210 / 1000+ resultsresearch Capture of endothelial cells under flow using immobilized vascular endothelial growth factor
In this study, immobilized VEGF selectively captured endothelial cells under various shear stresses, suggesting its potential for promoting endothelialization in vascular grafts or implanted tissues.
research Baricitinib-loaded EVs promote alopecia areata mouse hair regrowth by reducing JAK-STAT-mediated inflammation and promoting hair follicle regeneration
This study investigated using baricitinib-loaded mesenchymal stem cell exosomes injected locally in an alopecia areata mouse model and found that this method improved hair regrowth better than baricitinib or exosomes alone, potentially offering a new therapeutic approach for treating alopecia areata.
research A 56-Day Randomized, Double-Blinded, and Placebo-Controlled Clinical Assessment of Scalp Health and Hair Growth Parameters with a Centella asiatica Extracellular Vesicle and Growth Factor-Based Essence
This study found that applying a topical scalp essence with Centella asiatica extracellular vesicles and growth factors significantly improved scalp health and hair growth compared to a placebo after 56 days.
research Small extracellular vesicles from mesenchymal stem cells: A potential Weapon for chronic non-healing wound treatment
This review discusses the therapeutic potential of mesenchymal stem cell-derived small extracellular vesicles for chronic wound treatment and reports no new clinical results, emphasizing the need for further research on their large-scale production and engineering.
research Multi-Herbal Extracellular Vesicle and Growth Factor Serum for Eyelash Care: A Pilot Randomized, Double Blind, Placebo-Controlled Clinical Study
This study found that a serum combining recombinant growth factors and plant-derived EVs significantly increased eyelash length and density without causing skin hyperpigmentation in healthy female participants over eight weeks.
research miR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells
This study found that extracellular vesicles from low-passage dermal papilla cells may activate hair growth by delivering miR-140-5p, which downregulates BMP2 signaling, suggesting potential therapeutic targets for alopecia.
research Novel Vegan Exosome-like Biomimetic Vesicles for Skin and Hair Follicle Protection and Rejuvenation: Structural and Functional Characterization and Placebo-Controlled Clinical Efficacy Studies
In this study, researchers developed vegan exosome-like vesicles from microalgae that mimic mammalian exosomes, demonstrating promising in vitro, ex vivo, and clinical effects such as improved wrinkle depth and elasticity, making them a potential alternative in cosmetic applications.
research In vivo delivery of CRISPR-Cas9 genome editing components for therapeutic applications
research In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers
This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.
research Epimedium brevicornum Maxim. Extract exhibits pigmentation by melanin biosynthesis and melanosome biogenesis/transfer
In this study, Epimedii Folium extract was found to enhance melanin production and promote pigmentation through mechanisms involving the MAPK/ERK1/2 pathway in both in vitro and in vivo models.
research Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs
This study validated a protocol for inducing surface ectoderm differentiation from human induced pluripotent stem cells and highlighted the role of TGFβ signaling pathways in this process.
research 060 Heterogeneity and lineage development of memory CD8+ T cells after viral infection of skin
research 0847 The addition of collagen scaffolds to human cell therapy to modify skin identity
Collagen scaffolds in cell therapy can transform skin to be more resilient and pressure-responsive.
research Dynamics and Epigenetics of the Epidermal Differentiation Complex
This review discusses recent insights into the dynamics and regulation of the epidermal differentiation complex during keratinocyte differentiation and reports no new experimental results.
research Research Progress of Extracellular Vesicles-Loaded Microneedle Technology
This review discusses the applications and potential of microneedles loaded with extracellular vesicles for tissue regenerative repair and disease diagnosis, but does not report new experimental findings.
research O04 HPV8 E6 leads to Lrig1+ keratinocyte stem cell expansion
This study found that the E6 gene, but not E7, was responsible for HPV8-induced expansion of keratinocyte stem cells in hair follicle junctional zones in mice.
research Vitadetect : Vitamin Deficiency Detection
In this study, researchers developed an AI-powered platform called VitaDetect, which screens for vitamin deficiencies using image analysis of nails, tongue, and skin, aiming to provide an accessible and early-stage detection tool in resource-limited settings.
research Harnessing Milk-derived Extracellular Vesicles for Oral Drug Delivery and Therapeutic Application
Milk-derived vesicles are promising for delivering drugs orally and treating various conditions.
research Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing
This review discusses the progress and challenges in delivering CRISPR/Cas9 systems for in vivo genome editing, highlighting current methods and opportunities for future therapeutic applications.
research 455 Beyond Immunity: TEC and JAK3 Kinase Activation in Melanocytes Drives Inflammation in Vitiligo
TEC kinases may help cause inflammation in vitiligo and could be targeted for treatment.
research Deletion of an Enhancer in FGF5 is Associated With Ectopic Expression in Goat Hair Follicles and the Cashmere Growth Phenotype
This study identified a 505-bp indel variant in the FGF5 gene associated with cashmere growth in goats, which may serve as a molecular marker in cashmere goat breeding programs.
research Erthwellness Discount Code "AVA25" Get 25% Off On All Products!
This document promotes a 25% discount using the code AVA25 on Erthwellness's natural health supplements, detailing how to apply the code and the benefits of their products, with no new research findings reported.
research Lentiviral Arrays for Live-cell Dynamic Monitoring of Gene and Pathway Activity During Stem Cell Differentiation
This study found that a lentiviral array of reporters can identify lineage-specific promoters and pathways in mesenchymal stem cell differentiation, aiding in the prediction of signaling pathway effects.
research 591 A New 3D Skin Model Containing Autologous Immune Cells Reconstructed by Tissue Engineering
This study developed a 3D skin model with immune and endothelial cells, which may enhance understanding of skin biology and diseases due to its closer approximation to native skin.
research Self-assembled monolayer enhanced support-free two-photon polymerisation for microscale kinematic pairs
This study introduced a high-viscosity epoxy photoresist to enhance the fabrication of complex microstructures with monolithic integration and mechanical stability, enabling advancements in two-photon 3D printing for creating functional micro-mechanical devices.
research Classification of Visually Similar Scalp Diseases using Deep Learning: A Hybrid CNN-VIT Approach with Cross-Attention Fusion
In this study, researchers developed a hybrid deep learning model called ScalpViT that accurately diagnosed scalp diseases with 94.3% accuracy, surpassing existing methods like ResNet-50 and EfficientNet-B3, and providing visual explainability for clinicians using GradCAM and Attention Rollout techniques.
research 603 Pathological modeling of epidermolysis bullosa simplex (EBS) using induced pluripotent stem cells (iPSC)
This study found that using human induced pluripotent stem cells (iPSC) carrying the causal mutation of Epidermolysis Bullosa simplex provides a robust model for understanding its molecular mechanisms and testing potential therapeutic targets.
research Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3
In this study, researchers successfully generated functional and long-lived melanocytes from human embryonic stem cells, demonstrating their biocompatibility and high engraftability in mice, which may aid in developing treatments for pigmentary skin disorders.
research Ixekizumab improves physical function, quality of life, and work productivity in biologic disease-modifying antirheumatic drug-naive patients with active psoriatic arthritis
Ixekizumab helps improve life quality, physical ability, and work performance in patients with psoriatic arthritis who haven't used biologic drugs before.