Pathological Modeling of Epidermolysis Bullosa Simplex Using Induced Pluripotent Stem Cells

    September 2019 in “ Journal of Investigative Dermatology
    M. Bonnette, Manoubia Saidani, Sophie Domingues, Gilles Lemaitre, N. Holic-Barlet, Annabelle Darle, Cécile Martinat, Christine Baldeschi
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    Studysummary This study found that using human induced pluripotent stem cells (iPSC) carrying the causal mutation of Epidermolysis Bullosa simplex provides a robust model for understanding its molecular mechanisms and testing potential therapeutic targets.
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