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research Pathological Modeling of Epidermolysis Bullosa Simplex Using Induced Pluripotent Stem Cells

September 2019 in “Journal of Investigative Dermatology”

Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.

research Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 in a Growth- and Stress-Dependent Fashion

30 citations , December 2011 in “Journal of biological chemistry/The Journal of biological chemistry”

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

research The Mixed Lineage Kinase Leucine-Zipper Protein Kinase Exhibits a Differentiation-Associated Localization in Normal Human Skin and Induces Keratinocyte Differentiation Upon Overexpression

17 citations , November 2000 in “Journal of Investigative Dermatology”

ZPK helps skin cells mature and may affect skin health.

research Editor's Evaluation: Plant Trans-Golgi Network/Early Endosome pH Regulation Requires Cation Chloride Cotransporter (CCC1)

September 2021

CCC1 is crucial for pH balance in plant cells, affecting growth and stress tolerance.

Differential Molecular Signature of Dermal Papilla Cells from Balding and Non-Balding Scalp in 2D, 3D Culture and Co-Culture with Adipose-Derived Stem Cells

research Differential Molecular Signature of Dermal Papilla Cells from Balding and Non-Balding Scalp in 2D, 3D Culture and Co-Culture with Adipose-Derived Stem Cells

September 2019 in “Journal of Investigative Dermatology”

Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.

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community Is it okay to start oral minoxidil with creatine?

in Research/Science 3 upvotes 1 month ago

Oral minoxidil and creatine can be used together, but it's advised to start one at a time to monitor side effects. Creatine may increase DHT levels, potentially causing more hair shedding, while minoxidil can lower blood pressure, so hydration and monitoring for dizziness are important.

community Why can’t we just do another creatine study?

in Chat 153 upvotes 11 months ago

Creatine may worsen hair loss in some, especially with androgenic alopecia, but evidence is mixed. Some users experience no hair loss when using creatine with minoxidil and finasteride, while others notice increased shedding.

community Stop Complaining about Creatine. You're just fixated on shedding.

in Research/Science 76 upvotes 10 months ago

Creatine is unlikely to cause hair loss as it does not raise DHT levels. Hair loss is more likely due to genetics, medications, or lifestyle changes.

community Topical T3 study - 1000% Growth. Anyone tried it?

in Research/Science 104 upvotes 4 years ago

The conversation discusses using T3 (triiodothyronine) as a topical treatment for hair growth, with some users noting it showed promising results in studies but lacked follow-up. Users express interest in trying T3 due to its potential effectiveness compared to Minoxidil.