Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.

This study found that implanting hair-follicle-associated pluripotent stem cell sheets facilitated wound healing and early macrophage activity while reducing inflammation in a diabetic mouse model, suggesting clinical potential for difficult-to-heal diabetic ulcers.

This study demonstrated that intraoperative bioprinting using a bioink with human adipose-derived extracellular matrix and stem cells achieved successful reconstruction of full-thickness craniomaxillofacial skin defects in rats, promoting wound closure, adipogenesis, and hair follicle-like structure formation within two weeks.

This study found that tdDPC-EVs significantly improved wound healing by enhancing angiogenesis through the KLF4/VEGFA axis, offering advantages over traditional DPC-EVs.

This study found that in a rat model, minoxidil promoted better wound healing through potential anagen hair growth effects, while dexamethasone suppressed wound healing by reducing collagen production.

This report discusses a case where pregnancy triggered the development of folliculitis decalvans, highlighting that systemic treatments are typically avoided during pregnancy in favor of topical medication.

This narrative review discusses the discovery of plasticity in epidermal stem cells using single-cell transcriptomics, but reports no new results; it highlights the potential implications for regenerative medicine.

This review discusses the mechanisms, applications, and research evidence of photobiomodulation, highlighting its efficacy, safety, and potential for standardized evaluation methods, but reports no new clinical results.

This review discusses the potential applications of platelet rich plasma in dermatology and cosmetology for conditions like alopecia and skin rejuvenation and reports no new clinical findings.

This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.

In this study, injecting platelet-rich plasma into the muscular layer of the intestinal wall in rabbits significantly reduced adhesion development compared to soaking methods, suggesting an improvement in anastomosis regeneration.

In this study, 3D planned resection and reconstruction for skull defects after resection of cSCC with bony invasion led to accurate procedures, though patient-specific factors should guide treatment decisions.

This review discusses the similarities between wound healing and embryonic development, focusing on signaling pathways and their potential for developing new wound healing strategies, and reports no new clinical results.

This chapter reviews traditional and tissue-engineered treatments for skin defects and discusses advances in bioengineered skin constructs, but it presents no new experimental results.

Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.

This study observed that both TCA (35%) and GA (70%) chemical peels improved skin morphology and stimulated bulge stem cells in albino rats, with no significant difference between the two agents.

This review discusses current advancements in mesenchymal stem cell-based therapies for skin repair and rejuvenation, focusing on therapeutic strategies, particularly highlighting the potential of neonatal and placenta-derived MSCs, and reports no new clinical results.

In this study, researchers developed a novel 3D bio-printed skin scaffold using exosomes from liver cells, which enhanced wound healing by promoting cell growth, angiogenesis, and reducing inflammation in large skin injuries, suggesting potential applications in treating chronic skin conditions.

In this study, both platelet-rich plasma gel and 1% phenytoin cream showed comparable results for wound healing in diabetic foot ulcers in rats, with PRP providing slightly advanced histological improvements; however, the differences were not statistically significant.

This review examines advancements in "smart" hydrogel dressings for complex wound healing, highlighting innovations in materials that provide multifunctionality, such as responsive drug delivery and regenerative capabilities. The study also addresses potential challenges in clinical application, like manufacturing and regulatory hurdles.

This study found that HAMA hydrogels promote faster healing of skin wounds in mice by enhancing the accumulation of anti-inflammatory macrophages and increasing type III collagen in the local wound environment.

This study discusses advancements in nanotechnology and theranostic dressings, which may significantly improve chronic wound care by effectively targeting biofilms and enabling real-time monitoring, although obstacles to broad applicability and sustainability remain.

This review summarizes the role of G-protein-coupled receptors in wound healing and reports no new clinical results, highlighting their importance in signaling pathways and recent discoveries in their functions.

In this review, the authors discuss recent advancements in underwater adhesion technologies, specifically highlighting mussel-inspired catechol-based adhesives, which offer strong underwater bonding through various interfacial interactions and the influence of dopamine-modified polymeric tissue adhesives.

This study found that a mesenchymal stromal cell-derived regenerative extracellular matrix (rECM) significantly accelerated wound closure and improved healing in diabetic mice, also enhancing nerve and blood vessel formation compared to controls.

This review explores the potential of mesenchymal stem cells in skin regeneration and rejuvenation, highlighting their ability to modulate immune response and enhance extracellular matrix strength but does not provide new clinical evidence.

In this study, researchers found that gentamicin-loaded exosomes derived from a bovine leukocyte spleen extract significantly enhanced antimicrobial activity and tissue regeneration in infected diabetic wounds, showing potential as an effective therapeutic strategy for diabetic foot ulcers by improving infection control and promoting healing.

This study found that a combination of five medicinal plants traditionally used in Chinese medicine significantly improved skin repair and delayed aging markers in laboratory models, suggesting synergistic anti-aging effects over individual ingredients.

This study explores the potential of platelet-rich plasma (PRP) as a novel adjuvant therapy for eczema, positing that it may alleviate inflammation, enhance skin barrier function, and reduce recurrence.

This review reports significant advancements in plastic surgery using stem cell therapies for aesthetic and reconstructive applications, including grafting and wound healing, though it underscores the need for continued research to address regulatory, ethical, and standardization issues.