152 citations,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” A new mutation in the Connexin 26 gene was found in a patient with KID syndrome, expanding the known disorders linked to this gene.
112 citations,
January 2004 in “The International journal of developmental biology” Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
105 citations,
October 2018 in “Nature” A small group of slow-growing cells causes basal cell carcinoma to return after treatment.
75 citations,
March 1998 in “Journal of Investigative Dermatology” The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
61 citations,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
45 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Understanding hair follicles through various models can help develop new treatments for hair disorders.
35 citations,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
29 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
16 citations,
December 2020 in “PloS one” Researchers found WNT10A to be a key gene in developing goat hair follicles.
9 citations,
August 2021 in “Journal of clinical medicine” Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.
7 citations,
August 2020 in “Genes” Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
5 citations,
January 2015 in “Case reports in medicine” A baby was diagnosed with IFAP syndrome due to a new genetic mutation, showing severe skin and developmental issues.
3 citations,
August 2023 in “Genes” The document concludes that various signaling pathways and genetic factors are crucial for chicken feather development, affecting poultry quality.
3 citations,
January 2023 in “International journal of molecular sciences” Certain miRNAs play a key role in the growth of cashmere by affecting hair follicle development and regeneration.
2 citations,
January 2023 in “Scientific Reports” HIF-1α is important for hair growth and could be a treatment target for hair loss.
1 citations,
January 2024 in “International journal of molecular sciences” TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
1 citations,
November 2022 in “International journal of molecular sciences” Human fetal placental stromal cell injections speed up healing and improve skin and hair recovery after radiation damage.
November 2023 in “Biomolecules” The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.
Melatonin increased the activity of a hair growth gene in Cashmere goats.
72 citations,
November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
53 citations,
January 2013 in “Journal of toxicologic pathology” The project created a standardized system for classifying skin lesions in lab rats and mice.
42 citations,
December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
23 citations,
October 2021 in “Cell Stem Cell” Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
22 citations,
December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
21 citations,
July 2022 in “Orphanet journal of rare diseases” New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
11 citations,
October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
9 citations,
June 2017 in “American journal of ophthalmology. Case reports” A new mutation in the CDH3 gene causes hair loss and vision problems in a young girl.
7 citations,
January 2023 in “Frontiers in Cell and Developmental Biology” Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.
7 citations,
May 2022 in “PLOS ONE” Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.
6 citations,
August 2020 in “Cell regeneration” Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.