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    Glossary Epigenetic Factors

    external influences that modify gene expression without altering DNA

    Epigenetic factors are external or environmental influences that can modify the way genes are expressed without changing the underlying DNA sequence. These factors can include diet, stress, and exposure to toxins, and they can affect how cells read genes, potentially leading to changes in physical traits or susceptibility to diseases like alopecia.

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    1. Understanding Pattern Hair Loss—Hair Biology Impacted by Genes, Androgens, Prostaglandins and Epigenetic Factors Indian Journal of Plastic Surgery · 2021 · 3 citations
    2. Facial skin aging: an integrative analysis of genetics, epigenetics, and lifestyle factors GeroScience · 2025
    3. Epigenetic regulation and factors that influence the effect of iPSCs-derived neural stem/progenitor cells (NS/PCs) in the treatment of spinal cord injury Clinical Epigenetics · 2024 · 13 citations
    4. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018
    5. The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates Nature cell biology · 2023 · 6 citations
    6. Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata Experimental dermatology · 2001 · 30 citations
    7. Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation Frontiers in Cell and Developmental Biology · 2026
    8. Epigenetic and Environmental Regulation of Skin Appendage Regeneration 2015
    9. Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Male Infertility Springer eBooks · 2015 · 2 citations
    10. Promoter Methylation Changes in KRT17: A Novel Epigenetic Marker for Wool Production in Angora Rabbit International journal of molecular sciences · 2022 · 2 citations
    11. 164 Epigenetic and transcriptional profiling of PBMCs in mild and severe alopecia areata using single-cell RNA-Seq and ATAC-Seq Journal of Investigative Dermatology · 2023
    12. Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets. PubMed · 2016 · 39 citations
    13. Skin Organogenesis and Dysmorphogenetic Factors in Skin Diseases (Review) Sovremennye tehnologii v medicine · 2018 · 1 citations
    14. Framing the Problem: The Mystery of Post-Finasteride Syndrome and Reasons to Suspect a Microbial Factor Zenodo (CERN European Organization for Nuclear Research) · 2026
    15. Framing the Problem: The Mystery of Post-Finasteride Syndrome and Reasons to Suspect a Microbial Factor Zenodo (CERN European Organization for Nuclear Research) · 2026
    16. Stem Cell Heterogeneity and Plasticity in Epithelia Cell Stem Cell · 2015 · 129 citations
    17. The Pathobiology of Skin Aging American Journal Of Pathology · 2020 · 122 citations
    18. Alopecia areata − animal models Clinical and Experimental Dermatology · 2002 · 69 citations
    19. Do Changes in Chromosomes Cause Aging? Cell · 1996 · 50 citations
    20. Deciphering the Complex Immunopathogenesis of Alopecia Areata International Journal of Molecular Sciences · 2024 · 45 citations
    21. De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes European Journal of Human Genetics · 2019 · 36 citations
    22. Distinct mechanisms underlie pattern formation in the skin and skin appendages Birth Defects Research · 2006 · 25 citations
    23. The Genetics of Human Skin Disease Cold Spring Harbor Perspectives in Medicine · 2014 · 24 citations
    24. Making Waves with Hairs 2004 · 18 citations
    25. Prevalence and characteristics of polycystic ovary syndrome in Brazilian women: protocol for a nation-wide case–control study BMJ Open · 2019 · 15 citations
    26. Novel Mutation in Sjögren-Larsson Syndrome Is Associated With Divergent Neurologic Phenotypes Journal of child neurology · 2012 · 15 citations
    27. Physiology and Medical Treatments for Alopecia Facial Plastic Surgery Clinics of North America · 2020 · 8 citations
    28. Polycystic ovarian syndrome: current understanding of pathogenesis, diagnosis and treatment Meditsinskiy sovet = Medical Council · 2021 · 5 citations
    29. Emerging Topics in Cardiometabolic and Psychologic Sequelae, Pathogenesis, and Treatment of Polycystic Ovarian Syndrome: A Review Children (Basel) · 2019 · 4 citations
    30. Debatable Topics in PCOS Patients InTech eBooks · 2018 · 2 citations