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Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Vitamin D and its receptor may help prevent skin cancer.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Deleting MED1 in skin cells causes hair loss and skin changes.

Dlx3 is essential for hair growth and regeneration.

Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.

Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.

CCL5 is important for the hair growth potential of human dermal papilla cells.

Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.

Stem cells can create hair follicles, potentially treating permanent hair loss, and healthy skin and hair depend on mitochondrial function and special fats.

Golden oyster mushroom extract may protect skin cells from aging by its antioxidant properties.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Modifying certain signals in the body can help wounds heal without scars and regrow hair.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.