September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.
23 citations,
March 2017 in “PTR. Phytotherapy research/Phytotherapy research” Butin is effective in treating vitiligo in mice.
2 citations,
May 2023 in “Experimental dermatology” New imaging techniques can assess and track changes in mouse acne without harm, aiding treatment choices.
December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting the CD271 gene in mouse skin cells leads to disorganized skin and increased hair growth, suggesting CD271 is important for skin health.
September 2019 in “Journal of Investigative Dermatology” Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
12 citations,
June 2020 in “Frontiers in Cell and Developmental Biology” The PP2A-B55α protein is essential for brain and skin development in embryos.
January 2011 in “The Chinese Journal of Dermatovenereology” Curcuma anti-acne gel effectively reduces acne symptoms.
13 citations,
January 2022 in “Stem cell reviews and reports” Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
2 citations,
November 2014 in “Journal of dermatological science” Adapalene 0.1% effectively reduces acne by decreasing comedones and altering skin properties.
164 citations,
March 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
11 citations,
January 2018 in “IET Nanobiotechnology” The scaffolds significantly sped up wound healing in dogs and were safe.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.
Exosomes from certain stem cells can promote hair growth and counteract hair loss caused by hormones by regulating growth factors and other cellular signals.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” EGFR deficiency causes significant changes in skin cells and hair follicles.
April 2023 in “Journal of Investigative Dermatology” Exosomes from certain stem cells can fight hair loss by promoting hair growth and maintaining the growth phase of hair.
October 2021 in “QJM: An International Journal of Medicine” The study evaluated the efficacy of Platelet-Rich Plasma (PRP) therapy on androgenic alopecia in male albino rats. Eighteen rats were divided into three groups: control, testosterone, and PRP. The PRP group showed a significant increase in the number of anagen hair follicles and epidermal thickness, and a decrease in telogen hair follicles, compared to the control and testosterone groups. Immunohistochemical analysis revealed an increase in Ki 67 positive basal epidermal cells in the PRP group. The results suggest that PRP injections may have a positive therapeutic effect on androgenic alopecia.
293 citations,
November 2011 in “Nature” The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
143 citations,
May 2017 in “Nature cell biology” Wounded skin cells can revert to stem cells and help heal.
96 citations,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
57 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
36 citations,
April 2013 in “Cell and Tissue Research” Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
25 citations,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
18 citations,
August 2014 in “International journal of pharmaceutics” Aging and sun damage do not increase the skin's absorption of certain sunscreens and drugs.
10 citations,
May 2021 in “Stem Cell Research & Therapy” Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.
7 citations,
November 2014 in “Histochemistry and Cell Biology” The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.
2 citations,
May 2022 in “The journal of immunology/The Journal of immunology” BST2 protein and certain T cells increase in early alopecia areata.
April 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” ASH2L is essential for skin and hair development.
May 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” p120-catenin helps control skin inflammation by regulating cadherin levels.
February 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Merkel cells stabilize nerve endings in the skin, and they change independently of each other.
January 2021 in “Figshare” Metformin helps regenerate hair follicles in lab conditions.