research Inductive Properties of Hair Follicle Cells
Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
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research A Model System to Analyze the Ability of Human Keratinocytes to Form Hair Follicles
Scientists developed a system to study human hair growth using skin cells, which could help understand hair development and improve skin substitutes for medical use.
research A Human Prenatal Skin Cell Atlas Reveals Immune Cell Regulation of Skin Morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Localization of Members of the Notch System and the Differentiation of Vibrissa Hair Follicles: Receptors, Ligands, and Fringe Modulators
Notch-related genes play a key role in the development and cycling of hair follicles.
research Expression Patterns of the Siah Genes in Postnatal Mouse Skin
The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.
research Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocyte Differentiation in Hair Follicle
A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
research The Potential Role of Acetylcholine Receptors in Acne Inversa Pathogenesis
Acetylcholine receptors might be involved in the development of acne inversa and smoking could worsen the condition.
research C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny
c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
research RANK as a Therapeutic Target in Cancer
RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
research Self-Organizing Hair Peg-Like Structures From Dissociated Skin Progenitor Cells: New Insights for Human Hair Follicle Organoid Engineering and Turing Patterning in an Asymmetric Morphogenetic Field
Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
research Emerging Role of ILK and ELMO2 in the Integration of Adhesion and Migration Pathways
ILK and ELMO2 help cells move and stick together, important for wound healing and hair growth.
research Generation of Hair Follicle Germs In Vitro Using Human Postnatal Skin Cells
Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
research Dynamic Expression Patterns of Tenascin, Proteoglycans, and Cell Adhesion Molecules During Human Hair Follicle Morphogenesis
Specific proteins and molecules play key roles in the development of human hair follicles.
research Tuning Wnt Signals for More or Fewer Hairs
Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.
research Dermal Papilla Cells Induce Keratinocyte Tubulogenesis in Culture
Skin cells can help create early hair-like structures in lab cultures.
research Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin
Lack of cystatin M/E causes thin hair and dry skin.
research Embryonic-Like Regenerative Phenomenon: Wound-Induced Hair Follicle Neogenesis
New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
research LGR5 Is a Conserved Marker of Hair Follicle Stem Cells in Multiple Species and Is Present Early and Throughout Follicle Morphogenesis
LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
research A Novel Actor in Skin Biology: The Mineralocorticoid Receptor
Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.
research The Origins of Skin Diversity: Lessons From Dermal Fibroblasts
New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
research Special Focus Issue: Transdermal, Topical, and Follicular Drug Delivery Systems
New drug delivery systems improve treatment effectiveness and patient experience.
research Hairless: A Nuclear Receptor Corepressor Essential for Skin Function
The Hairless gene is crucial for healthy skin and hair growth.
research Cutaneous Adverse Effects of Targeted Therapies
Targeted cancer therapies often cause serious skin problems that need careful management.
research SOX2 in the Skin: Roles in Biology and Pathology
SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
research Targeted Deletion of Crif1 in Mouse Skin Epidermis Impairs Skin Homeostasis
Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.
research Regenerating Hair Follicles
Healing skin wounds in mice can create new hair follicles, and adjusting Wnt signaling could potentially reduce scarring and treat hair loss.
research Cosmetics, Hair, And Nails
Hair and nails are skin parts that develop early and serve protective and functional roles.
research Obstetric and Gynecologic Dermatology
A pregnant woman's skin condition improved after giving birth, possibly due to high estrogen levels during pregnancy.
research Advanced Therapies for Skin Injuries
New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
research Skin Fibroblast Heterogeneity and Plasticity Are Determined by the Local Niche
Mouse skin fibroblasts vary in function and adaptability based on their environment.