TLDR A girl with Becker's nevus syndrome showed good improvement in breast development using spironolactone.
Becker's nevus syndrome, part of the epidermal nevus syndromes, was described with a phenotype including Becker's nevus, ipsilateral breast hypoplasia, and variable skeletal malformations. It was more frequent in males (5:1) but more relevant in females. Diagnosis was clinically based on the presence of the skin lesion, with no established numbered criteria. Treatment for breast hypoplasia using 50 mg/day of spironolactone, an antiandrogen medication, demonstrated adequate clinical response.
Cited in this study
2 / 2 results
21 citations
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June 2010 in “Anais Brasileiros De Dermatologia” The document reports the first Brazilian case of a girl with Becker nevus syndrome, characterized by skin changes, breast underdevelopment, and scoliosis.
29 citations
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February 2003 in “Journal of Dermatology” Spironolactone may help enlarge a small breast linked to Becker's nevus.
7 citations
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January 2016 in “Case reports in pediatrics” A girl with Becker's nevus syndrome showed good improvement in breast development using spironolactone.
165 citations
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February 1994 in “Fertility and Sterility” Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.
26 citations
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January 1994 in “Hormone and Metabolic Research” Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.
