research Cell Death in Skin Function, Inflammation, and Disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
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510-540 / 1000+ results research Topical Polyhydroxy Acid Treatment for Autosomal Recessive Congenital Ichthyosis in the Golden Retriever: A Prospective Pilot Study
Gluconolactone products can significantly reduce skin scaling in golden retrievers with ARCI.
research Intercellular Adhesion Molecule-1 and Hair Follicle Regression
ICAM-1 helps regulate hair growth cycles and skin remodeling.
research Evo Devo of the Vertebrate Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Impact of Constant Light Exposure During Pregnancy on Skin of Neonatal New Zealand Rabbits: Structural and Ultrastructural Study
Constant light exposure during pregnancy changes newborn rabbits' skin, affecting hair follicles, skin thickness, and pigment cells.
research Fibroblast State Switching Orchestrates Dermal Maturation and Wound Healing
Fibroblast state switching is crucial for skin healing and development.
research Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions
Spermidine may help reduce hair loss and deserves further testing as a treatment.
research 17β-Estradiol Inhibits the Production of RANTES in Human Keratinocytes
17β-estradiol can reduce inflammation in the skin.
research The PDE4 Inhibitor, Apremilast, Suppresses Experimentally Induced Alopecia Areata in Human Skin In Vivo
Apremilast may help treat hair loss in alopecia areata.
research Molecular Basis of Androgenetic Alopecia
research Shedding Light on the Effects of Calorie Restriction and Its Mimetics on Skin Biology
Eating fewer calories may slow skin aging and improve skin health through various biological changes.
research Short Communication: Temporal Changes in the Skin Morphology of Dairy Cows During the Periparturient Period
Dairy cows' skin and hair follicles change size and growth phase around the time they give birth.
research Drugs and Androgenetic Alopecia: What to Look Out For
Certain drugs can worsen hair loss in people prone to androgenetic alopecia.
research Seborrheic Dermatitis and Pityriasis Sicca: A Review
Seborrheic dermatitis and dandruff are often treated with antifungal and anti-inflammatory medications, which can reduce symptoms and yeast growth on the scalp.
research Determination of the Factors Affecting the Frequency of Chemotherapy-Induced Alopecia and Methods of Coping with Alopecia
Most women undergoing chemotherapy experience hair loss, and many cope by using wigs or bonnets.
research Drug Repurposing Against KRAS Mutant G12C: A Machine Learning, Molecular Docking, and Molecular Dynamics Study
Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.
research Lymphocytes, Neuropeptides, And Genes Involved In Alopecia Areata
Alopecia areata is an autoimmune disease where T cells attack hair follicles.
research Integrin Signaling Regulates YAP/TAZ to Control Skin Homeostasis
The study demonstrated that the transcription regulators YAP and TAZ were essential for maintaining skin homeostasis by promoting the proliferation of basal layer stem/progenitor cells. In both mouse and human skin, YAP and TAZ localized in the nucleus of basal layer cells, regulated by integrin-Src signaling. Deletion of YAP and TAZ in mice resulted in slowed cell proliferation, hair loss, and impaired wound healing, underscoring their role in skin regeneration. The research highlighted the importance of integrin-Src and EGFR-PI3K signaling pathways for YAP nuclear localization, which was crucial for cell cycle progression and growth. Additionally, YAP acted as a sensor of epithelial cell polarity, with its localization influenced by apical-basal polarity signals. These findings provided insights into the molecular mechanisms of skin renewal and the potential impact of YAP and TAZ on skin-related conditions and cancer.
research Ethosomes: New Prospects in Transdermal Delivery
Ethosomes can safely and effectively deliver various drugs deep into the skin.
research Seaweeds as Source of Bioactive Substances and Skin Care Therapy: Cosmeceuticals, Algotherapy, and Thalassotherapy
Seaweeds have beneficial compounds for skin care, including anti-aging and protective effects.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System
Cannabinoids may help treat various skin conditions.
research Mammalian Keratin-Associated Proteins (KRTAPs) Subgenomes: Disentangling Hair Diversity and Adaptation to Terrestrial and Aquatic Environments
Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.
research The Chemokine SDF-1/CXCL12 Regulates the Migration of Melanocyte Progenitors in Mouse Hair Follicles
SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
research Frontiers in Alopecia Areata Pathobiology Research
The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
research Herbs for Benign Prostatic Hyperplasia
Herbal treatments can help with early-stage BPH symptoms, but more research is needed.
research Hydroxyl Radical Mediates Cisplatin-Induced Apoptosis in Human Hair Follicle Dermal Papilla Cells and Keratinocytes Through Bcl-2-Dependent Mechanism
Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.
research Identification of Sirtuin 1 as a Promising Therapeutic Target for Hypertrophic Scars
Sirtuin 1 could be a potential drug target for treating hypertrophic scars.
research Alopecia Areata: An Autoimmune Disease of Multiple Players
Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.
research Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hedgehog Signaling Pathway
The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
research MSCs and Their Exosomes: A Rapidly Evolving Approach in the Context of Cutaneous Wound Therapy
MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.