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The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

Ficus carica extract improved fertility in rats and may help with certain health conditions.

Expanded CD8+ T cells are linked to Alopecia Areata and may cause relapse after treatment.

Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.

The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

Myositis in lupus patients is linked to skin rash, hair loss, blood issues, and high disease activity.

Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

PCOS affects fertility and is linked to obesity and menstrual irregularities; lifestyle changes are recommended for treatment.

Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.

A specific genetic change is linked to mental disorders, intellectual disability, and possibly autoimmune disease in a family.

Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Changes in KRT17 gene activity linked to wool production in Angora rabbits.

Certain miRNAs are linked to chicken feather development.

Acne is strongly linked to high BMI, hair loss, menstrual issues, family history, and eating too many sweets and fatty foods, but not to excessive hair growth.

Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.

Telogen effluvium is linked to deficiencies in iron, vitamin B12, and thyroid function.

Agmatine may help reduce seizures linked to hormone changes in female rats.

Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.

The KRT84 gene is linked to better wool quality in Gansu Alpine Fine-wool sheep.

Lower vitamin D levels are linked to higher CRP levels in people with a type of hair loss called alopecia areata.

Higher SHBG levels are linked to less severe hair loss in women, but vitamin D levels don't seem to affect hair loss.

A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.

Certain genes in Iranian sheep are linked to wool production and heat adaptation.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.