Serum Dihydrotestosterone Levels Are Associated With Adverse Myocardial Remodeling in Patients With Severe Aortic Valve Stenosis Before and After Aortic Valve Replacement
October 2022
in “
American journal of physiology. Heart and circulatory physiology
”
dihydrotestosterone DHT myocardial hypertrophy myocardial remodeling aortic valve stenosis SAVR left ventricular muscle mass fibrosis left ventricular function moesin vimentin heart muscle thickening heart muscle remodeling aortic valve narrowing surgical aortic valve replacement heart muscle mass heart tissue scarring heart function
Studysummary This study found that in patients with severe aortic valve stenosis, higher serum dihydrotestosterone levels were associated with increased myocardial hypertrophy, fibrosis, and reduced left ventricular function.
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