56 citations
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October 2007 in “Journal of Biological Chemistry”
This study concluded that dilated cardiomyopathy in Ctsl-deficient mice is mainly due to the lack of cathepsin L in cardiomyocytes, with additional heart stress from the fur defect.
January 2026 in “American Journal of Translational Research”
In this study, the combination of metoprolol and spironolactone in patients with coronary heart disease and heart failure significantly improved cardiac function and reduced inflammation and oxidative stress markers compared to spironolactone alone, with better clinical efficacy and fewer adverse effects.
In this study, injection of hair keratin artificial material into rats did not significantly affect leucocytes or blood plates compared to normal saline, suggesting its histocompatibility.
This study found that tamsulosin and finasteride may improve cardiac function and reduce prostatic volume in elderly male patients with chronic heart failure and benign prostatic hyperplasia.
Scientists have successfully grown functional hair follicles in the lab, marking a significant advancement in hair regeneration research. A user shared their personal experience with hair loss treatments, including Minoxidil and Finasteride, and plans to share a detailed protocol for hair restoration.
Dutasteride is considered a stronger alternative to finasteride for hair loss, with mixed results; some users report improvement, while others experience worsening or side effects. Effectiveness varies, with genetics and individual responses influencing outcomes.
DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.
Stopping finasteride often restores sexual function, with many experiencing improved libido and erections. Some users switch to minoxidil or topical finasteride to manage side effects while maintaining hair health.
What are the side effects of minoxidil, and can oral minoxidil affect your heart?Minoxidil can cause side effects, and because it was designed as a blood-pressure drug, some of them involve the heart and circulation. Published studies of low-dose oral minoxidil describe mostly mild problems, but fluid around the heart, pericarditis and other serious events have been reported, and the long-term picture is still being studied. Do not start, stop or change minoxidil without a doctor, and if you develop chest pain, a racing heartbeat, shortness of breath, fainting, swelling or rapid weight gain while using it, stop and seek medical care.