Anti-Androgenic Therapy with Finasteride in Patients with Chronic Heart Failure – A Retrospective Propensity Score Based Analysis

    July 2019 in “ Scientific Reports ”
    Badder Kattih, Lukas Simon Elling, Christel Weiss … Joerg Heineke
    Studysummary In this study, anti-androgenic therapy with finasteride for prostate disease was associated with reduced cardiac hypertrophy in heart failure patients, encouraging further investigation in larger cohorts.
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    Research cited in this study 5

    1. The Cardiovascular Safety of Dutasteride ˜The œJournal of urology/˜The œjournal of urology · 2016
    2. Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction Circulation · 2015
    3. The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer, and Depression Korean Journal of Urology · 2014
    4. Dihydrotestosterone: A Culprit in Left Ventricular Hypertrophy International Journal of Cardiology · 2012
    5. Testosterone, Cytochrome P450, And Cardiac Hypertrophy The FASEB Journal · 2002

    Related research 1

    1. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992