Anti-Androgenic Therapy with Finasteride in Patients with Chronic Heart Failure – A Retrospective Propensity Score Based Analysis

July 2019 in “ Scientific Reports ”

Badder Kattih, Lukas Simon Elling, Christel Weiss, Marieke Bea, Carolin Zwadlo, Udo Bavendiek, Johann Bauersachs, Joerg Heineke

finasteride anti-androgenic therapy Propecia

TLDR Finasteride helps reduce heart enlargement in heart failure patients.

The study investigated the effects of finasteride, an anti-androgenic drug used for prostate disease, on cardiac hypertrophy and heart failure in patients. The retrospective analysis of 1041 medical cases with heart failure found that anti-androgenic therapy with finasteride was associated with significantly reduced left ventricular hypertrophy in patients with heart failure. The study suggests that further analysis of this approach in larger heart failure patient cohorts is encouraged.

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Research cited in this study

3 / 3 results

research The Cardiovascular Safety of Dutasteride

13 citations, May 2017 in “The Journal of urology/The journal of urology”

Dutasteride is as safe for the heart as finasteride.

research Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction

56 citations, January 2015 in “Circulation”

Finasteride helps reduce heart issues and improves heart function.

research The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer, and Depression

75 citations, January 2014 in “Korean Journal of Urology”

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

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community 2020 updated guide for "I'm losing my hair, what do I do?". I've been taking Propecia for 12 years, and you can AMA.

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Hair loss treatments discussed include Propecia, Rogaine, Nizoral shampoo, and dermarolling. Users shared experiences and results, with some noticing improvements in hair growth and maintenance.

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in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

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The conversation is about a finding that finasteride does not significantly increase the risk of sexual dysfunction, with users sharing mixed personal experiences regarding side effects.

Related Research

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research Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men

30 citations, August 1992 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride doesn't affect hormone levels in normal men.