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      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

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      community Huberman tweet about finasteride

      in Finasteride/Dutasteride  278 upvotes 1 year ago
      The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

      community My first 3 months battle against hairloss

      in Is this regrowth?  327 upvotes 4 months ago
      The user experienced significant hair regrowth over three months using 1.25mg oral finasteride, 5mg oral minoxidil, and weekly dermarolling. Initial side effects included mood swings, but these stabilized over time.

      community I hope ET-02 or PP405 will be released in the next 4-5 years

      in Product  15 upvotes 4 months ago
      PP405 is a potential hair loss treatment that may work by blocking signals that cause hair cells to stop growing, requiring daily application for effectiveness. It could serve as an alternative to minoxidil and finasteride, but it is not yet available on the market and may take several years to be released.

      community Where to Begin with Microneedling?

      in Treatment  17 upvotes 2 years ago
      User is considering microneedling to enhance hair regrowth after limited response to minoxidil and better results with finasteride and ketoconazole shampoo. Recommendations include using a 1.5mm derma roller once a week, avoiding minoxidil on microneedling days, and disinfecting the roller with isopropyl alcohol.

      community Verteporfin and Microneedling

      in Treatments 1 year ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.