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Serum Dihydrotestosterone Levels Are Associated With Adverse Myocardial Remodeling in Patients With Severe Aortic Valve Stenosis Before and After Aortic Valve Replacement

research Serum Dihydrotestosterone Levels Are Associated With Adverse Myocardial Remodeling in Patients With Severe Aortic Valve Stenosis Before and After Aortic Valve Replacement

4 citations, October 2022 in “American journal of physiology. Heart and circulatory physiology”

Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.

Immune Deficiency-Related Enteropathy-Lymphocytopenia-Alopecia Syndrome Results from Tetratricopeptide Repeat Domain 7A Deficiency

research Immune Deficiency-Related Enteropathy-Lymphocytopenia-Alopecia Syndrome Results from Tetratricopeptide Repeat Domain 7A Deficiency

64 citations, August 2014 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

research Gene Expression During Drosophila Wing Morphogenesis and Differentiation

57 citations, July 2005 in “Genetics”

Key genes are crucial for Drosophila wing development and could be insecticide targets.

research An Overview of JAK/STAT Pathways and JAK Inhibition in Alopecia Areata

40 citations, August 2022 in “Frontiers in immunology”

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications

39 citations, April 2020 in “IntechOpen eBooks”

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Exploring Bryan Johnson's Hair Routine In Detail

in Research/Science 65 upvotes 10 months ago

Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.