TLDR Certain genes in Iranian sheep are linked to wool production and heat adaptation.
The study analyzed the genetic data of 324 sheep from three Iranian breeds (Moghani, Afshari, and Gezel) and compared them with commercial breeds to identify genes associated with wool production and adaptation to harsh environments. Using Fst and nucleotide diversity statistics, the researchers identified several candidate genes, including KRTAP20-2, PTPN3, LHX2, COL17A1, CORIN, CPQ, PLCB4, FAM107B, PIK3C2B, and USP43. These genes are linked to traits such as wool fiber curvature, crimp traits, and heat stress adaptation. The findings suggest potential targets for breeding programs, though further research is needed to confirm phenotype-genotype relationships.
37 citations,
May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
117 citations,
November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
5 citations,
November 2022 in “Animal Genetics” Genomic research can help improve the quality and production of natural fibers in animals.
20 citations,
June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
7 citations,
January 2019 in “Journal of clinical medicine research” Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.
610 citations,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.