73 citations
,
September 2003 in “Journal of Pharmacology and Experimental Therapeutics” Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.
70 citations
,
August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
68 citations
,
January 2012 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
67 citations
,
January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
63 citations
,
December 2013 in “Dermatologic Surgery” Platelet-Rich Plasma (PRP) increases the number of new hair follicles and speeds up hair formation.
58 citations
,
January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
57 citations
,
March 2019 in “Journal of The American Academy of Dermatology” Platelet-rich plasma treatment can significantly increase hair count and density in men with pattern baldness, and these improvements can last up to 3 months.
53 citations
,
April 2014 in “Growth Hormone & IGF Research” IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
52 citations
,
February 2018 in “Diabetology & Metabolic Syndrome” Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.
51 citations
,
May 2011 in “Phytotherapy Research” Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
50 citations
,
March 2014 in “Stem Cells” Stem cell niches are adaptable and key for tissue maintenance and repair.
48 citations
,
June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
44 citations
,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
43 citations
,
July 2016 in “Clinics in Plastic Surgery” The conclusion is that fat grafting is safe and effective but carries risks that need careful management.
42 citations
,
December 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” New hair products are being developed to keep hair and scalp healthy for everyone.
41 citations
,
July 2015 in “Current Drug Discovery Technologies” Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.
39 citations
,
May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
39 citations
,
August 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
37 citations
,
January 2019 in “Food science & nutrition” Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.
37 citations
,
January 2015 in “Evidence-based Complementary and Alternative Medicine” An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
35 citations
,
August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
35 citations
,
December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
32 citations
,
June 2015 in “PLOS ONE” Olive leaf compound oleuropein helps grow hair in mice.
28 citations
,
December 2020 in “Gene” The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.
28 citations
,
September 2013 in “Expert Opinion on Therapeutic Patents” New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
26 citations
,
September 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
25 citations
,
September 2018 in “Scientific Reports” Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.
24 citations
,
October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
23 citations
,
November 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
22 citations
,
February 2017 in “Clinical and Experimental Dermatology” Icariin helps mouse hair grow by boosting a growth factor in skin cells.