Bibliometric Study of Adaptogens in Dermatology: Pharmacophylogeny, Phytochemistry, and Pharmacological Mechanisms
February 2023
in “
Drug Design Development and Therapy
”
adaptogens antioxidant activity hypothalamic-pituitary-adrenal axis neuro-endocrine-immune system grapes curcumin ginseng atopic dermatitis acne psoriasis androgenetic alopecia anti-aging anti-inflammatory anti-hair loss Panax ginseng Rhodiola rosea L. Eleutherococcus senticosus oxidative stress inflammatory factors skin homeostasis grape extract turmeric Korean ginseng Siberian ginseng golden root hair loss skin inflammation skin aging
TLDR Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.
The document discusses the potential applications of 109 plant adaptogens in dermatology, focusing on their antioxidant activity and their effects on the hypothalamic-pituitary-adrenal axis and the neuro-endocrine-immune system. These adaptogens, which include substances from grapes, curcumin, and ginseng, have been used to treat skin diseases like atopic dermatitis, acne, psoriasis, and androgenetic alopecia, and have shown anti-aging, anti-inflammatory, and anti-hair loss effects. The document also highlights the use of adaptogens in cosmetics, particularly Panax ginseng, Rhodiola rosea L., and Eleutherococcus senticosus, for their anti-aging and hair growth promotion properties. The document concludes that plant adaptogens can improve the regulation of oxidative stress and inflammatory factors, maintain skin homeostasis, and aid in the treatment of skin diseases. However, more research is needed to understand their mechanisms of action and efficacy.
