301 citations,
February 2019 in “Nature Communications” The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
31 citations,
September 2012 in “Journal of biological chemistry/The Journal of biological chemistry” The right amount of retinoic acid is essential for normal hair growth and development.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
1 citations,
December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Keeping β-catenin levels high in mammary cells disrupts their development and branching.
68 citations,
December 1991 in “Annals of the New York Academy of Sciences” Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
13 citations,
May 2005 in “Seminars in Plastic Surgery” Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.
179 citations,
April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
60 citations,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
December 2012 in “Journal of Dermatological Science” Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
223 citations,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
170 citations,
July 2012 in “Journal of Investigative Dermatology” Wnt ligands are crucial for hair growth and repair.
87 citations,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
74 citations,
January 2013 in “Expert Opinion on Biological Therapy” The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.
65 citations,
September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
57 citations,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D receptor is crucial for starting hair growth after birth.
18 citations,
February 2019 in “Scientific Reports” Trichostatin A helps restore hair-growing ability in skin cells used for hair regeneration.
8 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
224 citations,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
139 citations,
July 1991 in “Journal of The American Academy of Dermatology” Understanding hair follicle anatomy helps diagnose hair disorders.
113 citations,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
68 citations,
August 2014 in “Stem Cells Translational Medicine” Dermal papilla cells help wounds heal better and can potentially grow new hair.
66 citations,
August 2001 in “Experimental Dermatology” Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.
46 citations,
March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
43 citations,
August 2018 in “Cell Stem Cell” Hoxc genes control hair growth through Wnt signaling.
29 citations,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
21 citations,
July 2006 in “Veterinary dermatology” CD34 marks potential stem cells in dog hair follicles.
18 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
13 citations,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
9 citations,
August 2013 in “Journal of Tissue Engineering and Regenerative Medicine” Transplanted baby mouse skin cells grew normal hair using a new, efficient method.