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This study demonstrates that transfected epidermal stem cells using a novel 3D transfection system significantly enhanced wound healing and may serve as an effective therapeutic agent and gene delivery method for wound treatment.

This study found that cysteine supplementation significantly increases keratin expression in human keratinocytes, and counteracts the negative impact of iron deficiency on keratin production by enhancing iron availability for cellular processes.

This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.

This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.

This study found statistically significant patterns in hair morphology and ultrastructure linked to biogeographic ancestry among European, African, and East Asian populations.

This review discusses the use of terpenes and invasomes as permeation enhancers for transdermal drug delivery, focusing on their potential applications in pharmaceutical formulations, but it reports no new experimental results.

This practical guide introduces methods to study human dermal white adipose tissue but does not report new clinical results, emphasizing available techniques and staining protocols.

This article series reviews volumetric restoration techniques for different facial regions by expert authors, offering assessments of specific products but provides no new clinical results.

In this study, the researchers found that transplanted hair follicles undergo significant morphological changes, including a thickened dermal sheath and increased hair shaft diameter, which are associated with altered follicular vascularization.

This study identified four proteins that differ between Type III and non-Type III hair in Yangtze River Delta white goats, contributing to understanding the development of high-quality brush hair.

This study found that a dissolvable microneedle device delivering rapamycin and epigallocatechin gallate nanoparticles significantly enhanced hair regrowth in C57BL/6 mice within 7 days, demonstrating increased hair shaft growth and follicle density with minimal inflammation compared to untreated mice.

This article outlines a protocol for scanning electron microscopy of murine skin and primary keratinocyte monolayers, providing a guide for sample preparation and examination.

In this study, desmopressin-loaded elastic liposomes (ODEL1) showed improved permeation and drug deposition across rat skin by altering the skin's cohesive energies and causing reversible changes on its surface.

This review study found that vesicular carriers like liposomes, niosomes, invasomes, and transferosomes can enhance drug penetration through follicles, benefiting treatments for alopecia, acne, and infections, as well as potentially facilitating systemic delivery of antihypertensive drugs and insulin.

This study observed that five out of fourteen individuals aged 13-16 years, who were homozygous for the p.C282Y mutation related to hemochromatosis, had increased liver and phlebotomy-mobilized iron levels.

In this study, an infection model using rabbits was developed for dermatophytosis by inoculating macroconidia of Microsporum species, showing that direct intradermal application effectively progressed to the skin invasion phase and highlighted the correlation between severity of symptoms and duration post-inoculation.

This study developed a nanoemulsion containing Minoxidil, which showed effective stability and significantly increased hair growth rates in pretreated mice, suggesting its potential for treating hair loss.

This study found that the new delivery system HL@Mi enhanced the skin penetration, local bioavailability, and safety of minoxidil, supporting improved hair growth in an androgenetic alopecia animal model.

In this study, ketoconazole-loaded transferosomes were developed and demonstrated improved hair growth compared to a commercially available ketoconazole product, with the formulation showing enhanced drug penetration and minimal skin irritation in vivo.

This study found that dutasteride-loaded transfersomes, compared to traditional liposomes, better target hair follicles by releasing the drug in a more controlled manner, as shown in vitro with enhanced follicular targeting (Tf = 0.32 versus 0.15, p < 0.005) using porcine ear skin.

This review discusses the design strategies and applications of long-acting polymeric microneedles, noting their potential to improve patient compliance and reduce side effects in chronic disease management, but reports no new experimental results.

This review discusses the potential of nanocarriers to enhance transdermal drug delivery and the combination of these carriers with physical methods, but it reports no new experimental results.

This study found that nanoemulsions of different sizes vary in their ability to penetrate skin layers, with smaller sizes aiding transdermal delivery and potential applications in transcutaneous immunization.

This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential for disease treatment, but notes challenges in their clinical application.

The researchers developed semi-dissolving microneedle patches using TEMPO-oxidized bacterial cellulose nanofibers, which allow effective transdermal drug delivery by forming micro-channels for large drug quantities, overcoming traditional microneedles' low drug loading.

In this study, a new formulation of all-trans retinoic acid bound to polyvinyl alcohol showed reduced skin inflammation and sustained drug release for up to six days compared to free ATRA in vitro and in vivo.

This review discusses the potential of microneedle arrays for drug delivery and in the cosmetic market, but reports no new clinical results; factors for commercial therapeutic use are explored.

This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.

This study found that the expression of laminin-511 and -332 was significantly increased in psoriasis skin lesions and may influence keratinocyte proliferation and apoptosis, suggesting a previously overlooked role in the disease's pathogenesis.

This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential and challenges for clinical application, but it reports no new clinical findings.