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This study found that ketorolac tert-butyl ester enhances skin permeation and follicular absorption compared to ketorolac, highlighting the role of lipophilicity and solubility in prodrug design.

This study found that using elastic nano-liposomes to deliver palmitoylethanolamide improved its transdermal delivery and enhanced its skincare effects, with minimal cytotoxicity and no allergic reactions observed.

This study in Hexi cashmere goats found that secondary follicle activity increases with time, and Hoxc13 expression varies significantly across different growth stages, suggesting a role in follicle activity.

This paper reviews the development of transdermal drug delivery systems for skin diseases, from first to fourth generation, and highlights ongoing challenges and the importance of clinical trials, but provides no new clinical results.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

This review article discusses recent advances in transdermal drug delivery using nanocomposite systems, which improve drug absorption and release across the skin, allowing both hydrophobic and hydrophilic drugs to be effectively delivered while minimizing side effects.

This review outlines the potential of nanoemulsion-based hydrogels (nanoemulgels) for enhanced topical and transdermal drug delivery in treating skin disorders, highlighting their ability to improve therapeutic efficacy, control drug release, and boost patient compliance.

This study found that cedrol nanoemulsions significantly promote hair follicle regeneration and reduce DHT levels in an androgenic alopecia mouse model, suggesting potential efficacy in AGA treatment.

This study involved formulating an invasome gel loaded with clotrimazole for treating fungal infections and assessed its various properties like spreadability and in vitro drug diffusion.

This study suggests that novel lipid nanoparticle formulations may be suitable for delivering anti-alopecia compounds like minoxidil and finasteride, although their skin penetration was limited.

This study found that both 5-ALA and Photofrin can effectively destroy human microvascular endothelial cells in vitro and cause tissue necrosis in vivo, with Photofrin showing greater efficacy at lower concentrations or power densities.

This chapter reviews dermatological drugs and cosmetics, identifying common allergens and preservatives linked to contact dermatitis without reporting new clinical results.

This review summarizes the application of microneedles in treating various skin diseases and highlights challenges like low drug loading, noting no new clinical results are reported.

This study concluded that a regimen of transdermal estradiol and oral medroxyprogesterone acetate effectively reduces hirsutism while minimizing side effects in women with polycystic ovary syndrome.

This review explores the applications of phytonutrient-based biosensors in micro-electrochemical systems and reports no new experimental findings, emphasizing the potential and challenges of this innovative approach.

This study reported that knocking out the HR gene in pigs using CRISPR/Cas9 led to hairless eyelids and abnormalities in the thymus and peripheral blood, suggesting pigs as a model for human HR-related hair disorders.

In this retrospective cohort study, no significant differences were observed in assisted reproductive outcomes among different PCOS phenotypes undergoing frozen-thawed embryo transfer.

In this study, researchers developed a three-dimensional ultrastructural analysis tool using serial block-face scanning electron microscopy to reveal detailed nerve networks and muscle structures in human skin tissues, demonstrating the technique's potential to study structural changes in aging or disease.

In this study, researchers developed a promising transdermal agent using Triton X-100-modified polyethyleneimine that successfully delivered genetic material to hair follicle cells in mice, potentially alleviating hair loss due to androgenetic alopecia by promoting cell proliferation and inhibiting apoptosis.

In this study, an 11-year-old girl with acrodermatitis enteropathica showed significant improvement in symptoms after oral zinc therapy.

This study developed a novel liposome-based delivery system for Minoxidil and nitric oxide, which showed promising results in promoting hair regrowth in an androgenetic alopecia model by enhancing transdermal absorption, prolonging skin retention, and reducing inflammation.

In this case report, an 11-year-old girl with acrodermatitis enteropathica experienced a complete resolution of symptoms following oral zinc therapy, highlighting its effectiveness in managing this condition.

This review discusses the application of lipid nanoparticles for enhancing drug delivery through hair follicles and reports no new clinical results, emphasizing the potential role of sebum-like lipids in this context.

This review examines physical methods like electron paramagnetic resonance spectroscopy, Raman spectroscopy, and differential scanning calorimetry, highlighting their complementary capabilities in analyzing biomolecular structures and mycobacterial interactions with reactive oxygen species and antioxidants.

This study found that bimatoprost eye drops increased eyelash length, thickness, pigmentation, and the number of eyelashes per follicle in rabbits, without causing inflammation.

This study found that bimatoprost eye drops significantly increased eyelash length, thickness, pigmentation, and the number of eyelashes per follicle in rabbits within one month.

This study found that mice with a mutation in the Zdhhc13 gene exhibited increased susceptibility to skin cancer, highlighting a potential protective role of palmitoyl acyltransferase in skin carcinogenesis.

This study demonstrated that a device combining hyaluronic acid-based dissolving microneedles and lipid polymer hybrid nanoparticles effectively delivered miR-218 to promote hair growth in a shaved mouse model, outperforming topical smear treatment without safety concerns.

The researchers reported that mast cell and nerve fiber interactions in mouse skin are highly selective for nerve fiber types and vary depending on the hair cycle phase.

This study observed that repeated low-depth microneedling in patients with androgenetic alopecia led to initial hair improvement but subsequently caused hair-shaft fragility and breakage, suggesting iatrogenic damage.