1 citations
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February 2026 in “ACS Nano” This study developed the TLMG hydrogel, a seamless in situ biointerface platform, demonstrating robust adhesion, high conductivity, and therapeutic effects for intelligent wound management in complex animal models and human tests, indicating its promise for integrated bioelectronic medicine.
1 citations
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July 2025 in “Chemosensors” This study developed a closed-loop system for emergency wound care that monitors infection in real-time using biomarkers and delivers amikacin-loaded liposomes for treatment, integrating a conductive hydrogel for environmental protection and antibacterial benefits.
24 citations
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January 2019 in “Biomaterials Science” This study demonstrated that a bio-3D printed artificial skin scaffold, seeded with adipose-derived mesenchymal stem cells, showed promising wound healing properties by enhancing cell recruitment, migration, and gene expression related to tissue regeneration.
March 2026 in “Journal of Biomedical Materials Research Part B Applied Biomaterials” This study found that a chitosan, chondroitin sulfate, and hyaluronic acid scaffold improved wound healing in rats by promoting immune-stromal interactions, reducing inflammation, and supporting tissue regeneration with ~91% wound closure by day 17 compared to ~63% in controls.
1 citations
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January 2019 in “Elsevier eBooks” This review discusses scaffold materials and properties used in epidermal tissue engineering to promote skin regeneration and reports no new research findings.
March 2024 in “International Journal of Drug Delivery Technology” This study reviews the potential of electrospun nanofiber mats as innovative drug delivery systems for wound healing, emphasizing their ability to enhance drug release, improve cell adhesion, and promote tissue regeneration by incorporating antibiotics, growth hormones, or stem cells.
July 2026 in “Acta Biomaterialia” This study introduced a bioengineering platform that creates early-stage hair peg-like structures within tissue-engineered skin substitutes by integrating human keratinocytes and dermal papilla cells with laser-micropatterned collagen scaffolds, providing a foundation for future appendage-inclusive skin regeneration efforts.
June 2024 in “Advanced functional materials” This study introduced a novel wound dressing combining liquid metal composite with electrical stimulation, which accelerated wound healing and promoted hair follicle regeneration in nine days, effectively reducing scarring compared to untreated wounds.
January 2026 in “SSRN Electronic Journal”
This study introduced a rapid rehydration approach for creating customizable, multifunctional hydrogel sensors, enabling precise detection of surface deformations and easy integration of layers, highlighting its potential for standardized and adaptable manufacturing of wearable devices.
70 citations
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August 2020 in “Nanomaterials” This review discusses the development of electrospun nanofibrous scaffolds for promoting angiogenesis in tissue engineering but notes that their clinical application beyond bone and skin repair is still limited.
61 citations
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April 2023 in “Advanced Materials” This study introduced a viscoelastic dry electrode that successfully reduces motion artifacts in EP monitoring on hairy skin, maintaining stable performance for up to 48 days.
March 2026 in “Chemical Engineering Journal” The hydrogel helps heal diabetic wounds by combining antibacterial, antioxidant, and immune-boosting effects.
In this study, a pH-responsive microneedle patch was developed, showing potential in rat models for treating spinal cord injuries by reducing inflammation, promoting nerve regeneration, and supporting neurogenesis, which contributed to improved motor and neurological recovery.
February 2024 in “Advanced Science” This study highlights that a novel radially aligned nanofiber scaffold with dual growth factor gradients significantly enhances wound healing, promoting cell migration, epidermal regeneration, and angiogenesis, ultimately leading to improved wound closure, immune regulation, and tissue remodeling compared to other groups.
August 2025 in “Journal of Polymer Science” This review reports that combining adipose-derived stem cells with decellularized extracellular matrix enhances tissue repair by improving scaffold biological activity and promoting angiogenesis, integration, and functional regeneration across various tissues, while addressing challenges in traditional transplantation methods.
6 citations
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July 2025 in “Advanced Materials” This review discusses cell membrane-coated scaffolds in tissue engineering, emphasizing their potential to enhance therapeutic outcomes in regenerative medicine and reporting no new experimental results.
1 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that D-peptide crosslinked MAP hydrogels accelerate skin regeneration and promote adaptive immunity, despite faster scaffold degradation in vivo.
198 citations
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May 2021 in “Advanced Materials” This review discusses triboelectric nanogenerator (TENG) devices for body-integrated electrical stimulation therapy and suggests they may revolutionize personalized healthcare, but it reports no new clinical results.
4 citations
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May 2012 in “Tissue Engineering and Regenerative Medicine” This study demonstrated the potential of epithelial cell scaffolds fabricated with various materials for effective hair regeneration, highlighting their promising application in tissue engineering for alopecia treatment.
7 citations
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June 2025 in “Nano Energy” This study reports that triboelectro-responsive DNA hydrogels, enhanced with conductive polymers and triboelectric stimulation, effectively accelerate wound healing and exhibit strong anti-bacterial and anti-inflammatory properties, achieving 99.8% closure of bacterium-infected diabetic wounds in 14 days.
8 citations
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May 2024 in “ACS Applied Materials & Interfaces” This study found that incorporating PCL-based nanoscaffolds into liver spheroids enhances their viability and liver-specific biofunctionality, suggesting these scaffolds improve the model's potential for preclinical drug screening by increasing sensitivity to acetaminophen toxicity compared to traditional methods.
1 citations
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March 2024 in “Nanomaterials” This review article summarizes recent advancements in biomimetic scaffolds, highlighting their promise in tissue engineering and personalized medicine, particularly for skin and musculoskeletal system regeneration, while emphasizing the need for more extensive research to ensure their safety for human use.
November 2025 in “Nanoscale Advances” This review highlights the potential of inorganic nanoparticle-based scaffolds as innovative tools for advanced wound care, emphasizing their ability to provide antimicrobial action and regenerative support, while also discussing fabrication strategies and challenges in optimizing their clinical application.
January 2012 in “조직공학과 재생의학” This study demonstrated the potential of newly fabricated epithelial cell scaffolds to enhance hair regeneration, showing promise for future alopecia treatments.
August 2023 in “Drug Delivery and Translational Research” Human hair keratin was used to create a scaffold that could help with skin repair.
2 citations
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December 2022 in “PÄDI Boletín Científico de Ciencias Básicas e Ingenierías del ICBI” This review provides an overview of composite scaffold materials for skin that mimic natural dermal tissue, and highlights their potential in treating chronic wounds like diabetic foot by promoting cellular growth.
June 2026 in “Chemical Engineering Journal”
17 citations
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June 2018 in “Frontiers in Physiology” This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.
July 2026 in “Advanced Healthcare Materials” This study developed ultrasound-responsive sutures that generate reactive oxygen species to kill bacteria without antibiotics, showing over 80% bacterial reduction and promoting healing in a rat model, though more validation is needed.