Fabrication and Characterization of Epithelial Scaffolds for Hair Follicle Regeneration
January 2012
in “
조직공학과 재생의학
”
TLDR The study found that certain three-dimensional scaffolds can help regenerate hair effectively.
In 2012, researchers attempted to enhance the hair inducing ability of epithelial cells and form functional epithelial structures by fabricating three-dimensional scaffolds using bladder submucosal membrane (BSM), keratin, hyaluronic acid (HA), and mouse newborn epithelial skin scaffold (NESS). They found that the BSM sponge activated melanocytes when the inductive dermal papilla sphere was inserted. The keratin fiber sheet enhanced cell spreading and adhesion more effectively than the HA sheet. Human outer root sheath keratinocytes formed a cluster on the NESS. These findings suggested the potential of epithelial cell scaffolds for effective hair regeneration.
