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In this study, researchers reported that adenosine stimulated hair shaft elongation in cultured human hair follicles by promoting proliferation and prolonging the anagen phase, suggesting the A2B adenosine receptor in outer root sheath keratinocytes as a promising target for treating hair growth disorders like alopecia.

This study found that a novel peptide, FOL-005, derived from osteopontin, significantly inhibited hair growth in human hair follicles both ex vivo and in vivo, suggesting potential as a treatment for unwanted hair growth.

This study found that the in vitro growth of hair follicle cells, particularly papilla cells and outer root sheath keratinocytes, is influenced by different concentrations of androgens and antiandrogens.

This study found that testosterone and dihydrotestosterone significantly decreased the proliferation of papilla cells compared to dermal fibroblasts and outer root sheath keratinocytes in cultured hair follicle cells.

This study found that hair follicle cells' growth in vitro is influenced by the concentration of androgens and antiandrogens, with papilla cells and outer root sheath keratinocytes showing distinct sensitivity.