research Pharmacokinetic-Pharmacodynamic Modeling Approach for Dose Prediction of the Optimal Long-Acting Injectable Formulation of Finasteride
Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.
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research Crystal Structure and Synthesis of 17α-Acetoxy-Pregn-4,6-Diene-3,20-Dione
The compound was successfully made and shows potential for treating prostate cancer.
research Towards Expansion of Human Hair Follicle Stem Cells In Vitro
Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
research In Situ Labeling of DNA Reveals Interindividual Variation in Nuclear DNA Breakdown in Hair and May Be Useful to Predict Success of Forensic Genotyping of Hair
In situ DNA labeling in hair can help predict forensic DNA analysis success.
research Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence
Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
research Sebocytes’ Makeup: Novel Mechanisms and Concepts in the Physiology of the Human Sebaceous Glands
Hormones and signaling pathways control sebaceous gland function and could help treat acne.
research Reassessing Frontal Fibrosing Alopecia
Frontal Fibrosing Alopecia is a slowly progressing hair loss condition, likely underdiagnosed, with ineffective treatments, needing more research to understand it fully.
research Influence of Substance P on Cultured Sebocytes
Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
research Hedychium Spicatum: A Systematic Review on Traditional Uses, Phytochemistry, Pharmacology, and Future Prospects
Hedychium spicatum has medicinal properties but needs more research for scientific validation and use.
research A Surge in the Incidence of Telogen Effluvium in Minority Predominant Communities Heavily Impacted by COVID-19
More people, especially Hispanic/Latinx, in certain NYC communities experienced temporary hair loss during the COVID-19 pandemic.
research Macroenvironmental Regulation of Hair Cycling and Collective Regenerative Behavior
Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
research Targeted Transfollicular Delivery of Artocarpin Extract from Artocarpus Incisus by Means of Microparticles
Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
research Interactions of the Vitamin D Receptor with the Corepressor Hairless
Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
research Management of Polycystic Ovary Syndrome in Women by Implementing a Healthy Lifestyle and Effective Diet: A Review
Eating healthy, exercising, and certain nutrients like myoinositol and omega-3s can help manage PCOS symptoms.
research Recent Advances in Oxasteroids Chemistry
New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
research Pilose Antler Extracts Promote Hair Growth in Androgenetic Alopecia Mice by Activating Hair Follicle Stem Cells via the AKT and Wnt Pathways
Pilose antler extracts help hair growth by activating hair follicle stem cells.
research Topical Application of Cyclosporin A Induces Rapid Remodeling of Damaged Anagen Hair Follicles in Cyclophosphamide-Administered Mice
Cyclosporin A helps damaged hair follicles regrow hair quickly.
research The Effect of Curcumin Supplementation on Circulating Adiponectin and Leptin Concentration in Adults: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials
Curcumin supplements increase adiponectin and decrease leptin in adults.
research Intradermal Injection in Balding Region Versus Intramuscular Injection in Surrounding Muscles: A Split-Scalp, Randomized Trial on Botulinum Toxin for Androgenetic Alopecia
Intramuscular injections improved hair density more than intradermal injections for treating hair loss.
research Histological Characteristics of Hair Follicles at Different Hair Cycle and In Vitro Modeling of Hair Follicle-Associated Cells of Yak (Bos Grunniens)
The study provides insights into hair growth mechanisms in yaks.
research Skin Biopsy
Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.
research The Effects of Temperature, pH, and Moisture Exposure on Human Hair
High temperatures, acidic conditions, and too much coconut oil damage hair, while a pH of 5 to 7 keeps it healthy.
research General Adverse Response to Cyclophosphamide in Chinese Patients with Systemic Autoimmune Diseases in Recent Decade: A Single-Center Retrospective Study
Cyclophosphamide often causes gastrointestinal issues, hair loss, and low blood cell counts in Chinese patients with autoimmune diseases.
research Structural Characterization of Cyclosporin A, C, and Microbial Bio-Transformed Cyclosporin A Analog AM6 Using HPLC–ESI–Ion Trap-Mass Spectrometry
Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.
research Three-Dimensional Reconstructions of Mechanosensory End Organs Suggest a Unifying Mechanism Underlying Dynamic, Light Touch
Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.
research Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction: Two Sides of the Same Coin?
PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
research Distinguishing Histopathologic Features of Acantholytic Dermatoses and the Pattern of Acantholytic Hypergranulosis
Different skin diseases show unique patterns of skin cell separation, cell death, and granular layer changes.
research Lymphatic Vasculature and Hair Follicle Regeneration
Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
research Particulate Matter 2.5 Damages Skin Cells by Inducing Oxidative Stress, Subcellular Organelle Dysfunction, and Apoptosis
Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
research Acanthosis Nigricans in the Knuckles: An Early, Accessible, Straightforward, and Sensitive Clinical Tool to Predict Insulin Resistance
Darkened knuckles can be an early sign of insulin resistance.