May 2023 in “Stem cell research & therapy” This study describes a novel method using force-triggered density gradient sedimentation for efficiently isolating dermal papilla cells from neonatal mouse skin, showing promise for hair follicle regeneration research.
January 2009 in “China Practical Medicine” This study found that several genes, including capping protein, palladin, VEGF, and HSPC-related clones, might cooperatively influence the aggregation, proliferation, and cycle control of dermal papilla cells, potentially affecting hair follicle behavior.
15 citations
,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” This study found that a newly developed hemi-vascularized sandwich method significantly improved the regeneration and maturity of hair follicles compared to other transplantation approaches in rat models.
2 citations
,
November 2024 in “Australian Journal of General Practice” This abstract highlights the urgent need for rigorous research, quality assessment tools, and health economics analyses to integrate DTC telemedicine with traditional primary care for improved healthcare quality and efficiency.
January 2005 in “Industrial Catalysis” This study found that regenerating the Pd/C finasteride synthesis catalyst using methanol extraction and nitric acid oxidation achieved a pregnendone conversion of 97.5%.
199 citations
,
April 2010 in “Nature” A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
12 citations
,
February 2013 in “The Open Stem Cell Journal” This article reviews the definitions, opportunities, advantages, and limitations of dental pulp stem cells and stem cells from human exfoliated deciduous teeth in tissue engineering and regenerative medicine, reporting no new clinical results.
29 citations
,
March 2010 in “Journal of Dermatological Science” This study found that Wnt3a increased beta-catenin signaling and upregulated specific genes in cultured human dermal papilla cells, enhancing their response to PGE2 and potentially aiding hair growth.
4 citations
,
January 1994 in “Yakugaku zasshi” In this study, EPC-K, a compound with antioxidant and moisturizing effects, was found to decompose significantly under certain conditions, impacting its stability in quasi drug hair-growing products.
July 2022 in “Dermatology Reports” This report details a case of a 58-year-old male diagnosed with erosive pustular dermatosis of the scalp, which improved following 3-5 weeks of treatment with topical clobetasol proprionate.
3 citations
,
September 2024 in “Journal of Microbiology and Biotechnology” This study found that human placenta hydrolysate effectively inhibited atopic dermatitis development in stimulated human cells and a mouse model, suggesting its potential as a therapeutic agent for related skin diseases.
13 citations
,
January 2014 in “Zhongguo zhongyao zazhi” This study found that Dendrobium candidum polysaccharides might promote hair growth in mice, potentially by increasing VEGF mRNA expression.
November 2024 in “Journal of Investigative Dermatology” Androgens reduce hair growth by affecting cell differentiation and blood vessel formation.
November 2018 in “Journal of Investigative Dermatology” Lichen Planopilaris causes irreversible hair loss due to immune attacks on hair stem cells, but modulating PPAR-γ might help treat it.
13 citations
,
June 2007 in “Journal of Dermatological Science” This study identified several genes regulated by dihydrotestosterone in an SV40T-transformed human dermal papilla cell line, which may play a role in androgen-mediated hair growth regulation.
18 citations
,
January 2020 in “Journal of the European Academy of Dermatology and Venereology” This study identified trichoscopy as a key diagnostic tool for erosive pustular dermatosis of the scalp and suggested high-potency steroids or tacrolimus as effective first-line treatments.
53 citations
,
September 2013 in “Journal of Investigative Dermatology” This study suggests that cultured hair follicle dermal sheath cup cells exhibit immune privilege properties, partly through the expression of PD-L1, which impacts co-cultured immune cells' behavior.
3 citations
,
May 2023 in “International Journal of Molecular Sciences” In this study, researchers observed that phospholipid-calcium carbonate hybrid nanoparticles effectively delivered Tofacitinib citrate topically, which significantly inhibited hair follicle apoptosis and promoted hair growth in a mouse model of chemotherapy-induced alopecia, compared to a traditional Tofacitinib solution.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that Derinat treatment in mice maintained the hair cycle in the anagen phase and reduced TRPCs-mediated intracellular ROS accumulation, potentially improving hair growth by altering the skin microenvironment.
January 2026 in “Cosmetics” This study reported that Cacumen Platycladi extract significantly reduced hair loss and increased hair density in a 12-week clinical trial, suggesting it may be a safe and effective natural treatment.
5 citations
,
January 2021 in “IEEE Access” In this study, researchers demonstrated that treating platelet rich plasma with microsecond pulsed electric fields effectively activates platelets and induces similar or higher growth factor release compared to traditional bovine thrombin, suggesting a potential clinical use that may be more cost-effective and practical.
October 2024 in “Cosmetics” In this study, subthermal RF-CRET currents were found to alter key molecular mechanisms in dermal papilla cells, promoting proliferation and survival while enhancing markers associated with hair growth and maintenance, suggesting potential benefits for hair regeneration.
53 citations
,
January 2011 in “Diabetes” The study found that severe insulin resistance and premature diabetes are common in patients with PCNT genetic defects, primarily affecting those over four years old, while not impacting early insulin signaling in adipocytes.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that prostaglandin D2 increases testosterone production in human keratinocytes through a mechanism involving ROS and REDOX potential, which could inform treatments for androgenic alopecia.
2 citations
,
June 2022 in “Cells” The study found that growing dermal papilla cells in 3D spheroids enhances their activity with hair growth-promoting agents, such as minoxidil and TCQA, compared to traditional 2D cultures.
3 citations
,
September 2017 in “Stem cell investigation” This review discusses the various roles of skin-resident dermal white adipose tissue in hair growth inhibition, antibacterial responses, and wound healing, reporting no new empirical findings.
34 citations
,
July 2013 in “Clinical Cosmetic and Investigational Dermatology” This study observed that while topical drug therapy for erosive pustular dermatosis rarely leads to complete resolution, surgery may achieve remission in male patients.
4 citations
,
June 2016 in “Journal of Pharmacopuncture” This study found that Cornu cervi pantotrichum pharmacopuncture solution significantly promoted hair growth in mice by enhancing hair follicular cell proliferation and up-regulating FGF-7 expression.
August 2026 in “Russian Journal of Skin and Venereal Diseases” In this prospective study, combining photodynamic therapy with PRP therapy significantly improved hair growth, quality of hair, and quality of life in women with acute telogen effluvium, compared to using each therapy alone.
50 citations
,
June 1999 in “Annals of Oncology” This study found that long-term weekly administration of docetaxel is feasible at doses up to 45 mg/m² per week with acceptable toxicity, and suggests further evaluation with 40 mg/m² for phase II studies.