Regeneration of Pd/C Finasteride Synthesis Catalyst by Extraction-Oxidation
January 2005
in “
Industrial Catalysis
”
New to Finasteride? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that regenerating the Pd/C finasteride synthesis catalyst using methanol extraction and nitric acid oxidation achieved a pregnendone conversion of 97.5%.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study investigated the regeneration of a Pd/C catalyst used in finasteride synthesis through an extraction-oxidation process. It was found that treating 1 g of used Pd/C catalyst with 30 mL of methanol at its boiling point for 60 minutes, followed by oxidation with 35% nitric acid at 80°C for 30 minutes, resulted in a pregnendone conversion rate of 97.5%. The research focused on optimizing the methanol amount, reflux time, and nitric acid concentration to achieve effective catalyst regeneration.
