384 citations
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January 2008 in “Journal of Internal Medicine” This review discusses the role of mitochondrial dysfunction in the ageing process and reports that its significance compared to other factors in mammalian ageing remains uncertain.
119 citations
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December 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, transcutaneously applied nanoparticles and viral vectors were shown to penetrate murine hair follicles, internalize in antigen-presenting cells, and induce immune responses, suggesting a promising approach for vaccine delivery.
37 citations
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January 1979 in “Archives of Dermatology” This case report suggests that PUVA treatment may have played a role in triggering systemic lupus erythematosus in a 23-year-old woman with psoriasis.
22 citations
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September 1998 in “PubMed” This study found that the water fraction of Panax ginseng may reduce apoptosis and enhance medullary cell formation in the hair follicles of irradiated mice, suggesting a potential protective effect.
16 citations
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August 2022 in “Nature Communications” In this study, researchers discovered that ROR2, a Wnt receptor, plays a crucial role in regulating hair follicle stem cell self-renewal and maintenance, compensating for the absence of β-catenin.
10 citations
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January 1994 in “Annals of Internal Medicine” This case report presents a young woman with systemic lupus erythematosus who was found to have CD4+ lymphocytopenia.
8 citations
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December 2003 in “Experimental Dermatology” In this study, injecting chimeric RNA–DNA oligonucleotides into mice skin caused a temporary mutation in keratin 17, altering hair morphology, but the mutation was transient due to genetic compensation or cell replacement.
6 citations
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February 2019 in “Journal of dermatology” This report details a rare case of favus in Japan, identifying Trichophyton schoenleinii in a 63-year-old woman through DNA sequencing, who was successfully treated with oral terbinafine and topical luliconazole.
6 citations
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May 2012 in “Archives of Dermatological Research” This study reports a novel missense mutation in the HR gene in a 68-year-old Hungarian woman with alopecia universalis and limb deformities, suggesting a need for further research on its role in these conditions.
4 citations
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June 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This case report describes a 30-year-old woman diagnosed with both Rhupus and Rowell syndromes, and details her presentation and treatment plan, without reporting specific treatment outcomes.
3 citations
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November 2022 in “The Egyptian Rheumatologist” This case report describes a rare instance where a young woman initially presented with macrophage activation syndrome as the first sign of systemic lupus erythematosus, and ultimately experienced multiorgan failure and death.
3 citations
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January 2022 in “Modern Rheumatology Case Reports” This case report details a rare instance of simultaneous onset of systemic lupus erythematosus and IgG4-related disease in a 73-year-old woman, where treatment improved symptoms by using high-dose glucocorticoids, hydroxychloroquine, and belimumab.
3 citations
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June 2020 in “Open access rheumatology” This case report reviews the management of Rowell syndrome in a patient initially diagnosed with Rhupus syndrome and highlights their development of erythema multiforme after certain medications.
2 citations
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January 2012 in “PubMed” This study found that mycophenolate mofetil is effective for both induction and maintenance therapy in children with severe lupus nephritis, significantly improving proteinuria and antibody levels, without renal flares during maintenance.
2 citations
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April 2011 in “InTech eBooks” This review discusses the potential skin care benefits of non-denatured soybean extracts, including skin lightening and UV protection, but reports no clinical results.
1 citations
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April 2025 in “Cureus” In this in vitro study, pretreatment with Dead Sea water and saline magnetized water reduced UVB-induced DNA damage and inflammation markers in human keratinocyte cells, primarily through autophagy activation, suggesting potential use in topical products to prevent skin damage from UV exposure.
1 citations
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April 2024 in “Food Frontiers” In this study involving mice, the researchers observed that circadian rhythm disorder can pass alopecia risk to male offspring, and parental Pu-erh tea consumption, particularly by females or both parents, mitigated this risk through various biological mechanisms.
1 citations
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February 2023 in “International Journal of Rheumatic Diseases” This study reported that tuberculosis can mimic lupus-like symptoms, including the production of autoantibodies, which may confuse the diagnosis with systemic lupus erythematosus flares.
1 citations
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January 2022 This case report describes a 29-year-old woman diagnosed with both systemic lupus erythematosus and Graves' disease, illustrating the occurrence of autoimmune polyendocrine syndromes with specific combinations of autoimmune disorders.
1 citations
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January 2021 in “Journal of the American Academy of Dermatology” This study found that bullous lupus erythematosus lesions in cutaneous lupus erythematosus showed distinctive histopathology with neutrophilic predominance and were associated with severe disease and higher extracutaneous involvement.
1 citations
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June 2016 in “Annals of the rheumatic diseases” In this study, researchers found that retinoids might improve lupus nephritis resistant to conventional treatments, but the sample size was too small for significant results, and side effects were noted.
This case report highlights the diagnostic challenge of ANA-negative pediatric SLE in South Asia, emphasizing the need for comprehensive diagnostic criteria and clinical vigilance for early recognition and treatment.
April 2025 in “Dermatología Argentina” This study found that simultaneous presence of specific and nonspecific skin lesions, or having three or more types of skin lesions, was associated with increased systemic activity of systemic lupus erythematosus.
March 2025 in “Mediterranean Journal of Rheumatology” This study concluded that laser hair removal using Alexandrite laser emitting red and infrared light appears safe and does not significantly affect the disease activity of Systemic lupus erythematosus.
In this pilot study, researchers found that ex vivo treatment with topical melatonin reduced chemotherapy-induced apoptosis and DNA damage in hair follicle stem cells of human scalp cultures, suggesting melatonin's potential as a protective agent against taxane-induced permanent hair loss.
April 2023 in “Journal of Investigative Dermatology” This pilot study suggests that topical melatonin may protect hair follicle stem cells from paclitaxel-induced damage, potentially preventing chemotherapy-induced alopecia and enhancing the effects of scalp cooling caps.
January 2023 in “Indian dermatology online journal” This case study describes a previously unknown association of the PIBIDS complex with autoimmune thyroiditis and autoimmune hemolytic anemia in a five-year-old Indian child.
October 2022 in “International journal of research in dermatology” This case report documents a 31-year-old woman with bullous SLE who showed improvement with high-dose parenteral steroids and dapsone, with ongoing follow-up due to potential kidney involvement.
This study found that in the Indian population, SLE patients with only skin manifestations often had a positive immunological profile, suggesting early identification of disease before systemic symptoms develop.
November 2021 in “Circulation” This case report highlights the first known instance of ANA-negative systemic lupus erythematosus presenting as spontaneous coronary artery dissection, emphasizing a need for rheumatological evaluation in such patients.