Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This case report describes a 7-year-old child with linear lupus panniculitis of the scalp, treated successfully with a combination of hydroxychloroquine, topical and intralesional steroids, and a topical calcineurin inhibitor.

This study found that among 26 pregnant patients with Systemic Lupus Erythematosus, the most common pregnancy complication was intrauterine growth restriction.

This study demonstrated that gene-corrected 3D skin constructs from RDEB patient-derived iPSCs, grafted onto immunocompetent mice, showed normal collagen VII expression after two months.

This study found that cutaneous manifestations, including specific skin lesions and oral ulceration, are common early indicators of SLE and may aid in its diagnosis and management.

This case report describes a teenager with Systemic Lupus Erythematosus experiencing neuropsychiatric symptoms, highlighting diagnostic criteria and laboratory findings, but reports no new treatment outcomes.

In this study, the authors found that a botanical extract with anti-inflammatory and anti-oxidative properties stabilized hair loss and preserved natural hair pigmentation and strength over six months.

This case report describes a 21-year-old man diagnosed with systemic lupus erythematosus, highlighting the condition's potential to mimic hematological malignancy and the effectiveness of prednisolone in rapid symptom improvement.

This study found that systemic lupus erythematosus in aging patients often presents with atypical clinical manifestations, leading to more frequent misdiagnosis, yet these patients may respond better to treatment.

This study found that intradermal injection of specific oligonucleotides altered hair growth and morphology in mice by inducing a dominant mutation in the K17 gene.

This study found that ROR2 plays a crucial role in the regulation of hair follicle stem cell self-renewal and maintenance, particularly by compensating for the absence of β-catenin.

This study found that TET2 plays a tumor-suppressive role in preventing squamous cell carcinomas by regulating 5-hydroxymethylcytosine levels, suggesting therapeutic potential for DNA methylation dynamics.

This review discusses advances in forensic DNA profiling, highlighting new genetic markers and methods for identifying unknown individuals, but reports no new research findings.

This article discusses how DNA-based phenotyping is used by police to create visual profiles of suspects from crime scene samples, but reports no new research findings.

Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.

This review compares DNA-derived biopolymers, PN and PDRN, in dermatology, emphasizing their distinct molecular characteristics and roles, and reports no new clinical results.

This article summarizes highlights from the 40th Annual DNA Convention, covering various dermatology topics, but it does not report new clinical results.

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

This study discovered that DNA damage independently induces IL-19 and IL-24 cytokines, which regulate senescence-associated secretory phenotype factors, suggesting potential pathways for treating cancer and age-related diseases.

This case study reported TSPyV DNA detection in blood and urine samples before trichodysplasia spinulosa skin lesions developed in a kidney transplant patient under immunosuppressive therapy.

This study found that synthetic RNA and DNA trigger significant increases in certain chemokines in human keratinocytes, predominantly via NF-κB activation, without evidence of alternative splicing, suggesting other regulatory pathways may be involved.

This study found that loss of the DNA methyltransferase Dnmt3a, but not Dnmt3b, increased carcinogen-induced squamous tumors in murine epidermis, with combined deletion leading to more aggressive and metastatic carcinomas.

This review highlights the significance and future potential of forensic DNA phenotyping for predicting human phenotypes from crime scene DNA but reports no new results.

This study found that inhibiting mTORC2 in glioblastoma cells reduced DNA repair and increased apoptosis, highlighting its potential role in cancer cell survival and DNA damage response.

This research discusses potential cancer vaccine strategies using cell-based and DNA vector-based approaches, and suggests targeting the v3 splice variant of thioredoxin reductase 1 to inhibit cancer cell motility and metastasis formation.

This review discusses the role of epigenetics in colorectal cancer and explains how changes like DNA methylation impact tumor development, but it reports no new results.

This study demonstrated that HOXC13 directly influences hair keratin gene expression by binding to specific DNA motifs, suggesting its role in early hair follicle differentiation.

This review discusses pyrene excimer nucleic acid probes for detecting biomolecules and protein-DNA interactions and reports no new experimental findings.

This review discusses how chronic inflammation can lead to persistent stem cell activation and DNA damage, ultimately promoting cancer development and metastasis, but reports no new results.

This study highlighted that advancements in genome-wide association studies have identified numerous DNA variants linked to human appearance traits, significantly enhancing our understanding of the genetic and epigenetic factors influencing human phenotypes and contributing to genomic tools for anthropology and forensics.

This study reports a method for fabricating biofunctional polymer fibers by using DNA-programmable cell-free protein synthesis integrated through solution blow spinning, enabling in situ protein production and potential applications in respirators, sampling swabs, and other advanced materials.