June 2018 in “Journal of Acupuncture and Meridian Studies” This study reports that an electrochemical biosensor using a gold and palladium-modified electrode effectively detects levodopa and uric acid in various samples, offering improved performance over previous electrodes.
April 2018 in “Journal of Investigative Dermatology” This study found that inhibiting NF-κB Essential Modulator (NEMO) in senescent murine dermal fibroblasts successfully reduced key factors associated with the senescence associated secretory phenotype (SASP), highlighting its potential as a therapeutic target for aging-related diseases.
February 2018 in “Chin J Clinicians(Electronic Edition)” This study found that rash in SLE patients is prevalent and associated with more severe disease indicators, including certain clinical manifestations and serological abnormalities.
January 2018 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” This thesis developed stimuli-responsive nanocarriers, demonstrating their potential for targeted genetic material delivery with reduced toxicity and diagnostic applications, and explored pH-sensitive nanogels for effective skin drug delivery and monitoring.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers found that SPF50+ sunscreens provided the highest DNA protection against solar-simulated radiation in a reconstituted human epidermis model, with formulation type not affecting efficacy for a given SPF.
September 2017 in “Journal of Investigative Dermatology” This study found that mackerel fermented fish oil protected human keratinocyte cells from UVB-induced oxidative stress by scavenging free radicals and reducing cellular damage.
September 2017 in “Journal of Investigative Dermatology” Loss of COL17A1 causes hair follicle stem cells to age and leads to hair loss.
April 2017 in “The FASEB journal” This study suggests that selenium deprivation in mice accelerates age-related degeneration but paradoxically promotes longevity, potentially decoupling healthspan from lifespan.
This study found that topically applied nano-Zinc oxide accumulated in hair follicles and induced apoptosis in hair follicle stem cells, indicating a potential risk to skin homeostasis.
September 2016 in “Journal of dermatological science” This study suggests that FGF18 may enhance radioresistance in telogen hair follicles by inducing cell cycle arrest, potentially serving as a radioprotector against radiation-induced hair follicle damage.
This review discusses the roles of epigenetic and environmental factors in the regeneration of skin appendages and highlights potential therapeutic approaches for conditions like alopecia.
January 2013 in “International Journal of Trichology” This case report describes a young girl with trichothiodystrophy and suggests the need for early diagnosis and multidisciplinary interventions for her educational challenges.
October 2012 in “Humana Press eBooks” This article discusses the historical and current uses of grape seeds in various industries but reports no new research findings.
April 2012 in “Neuropediatrics” This article reviews the genetic and phenotypic characteristics of Trichothiodystrophy and discusses the associated DNA repair defects, but does not report new clinical findings.
January 2012 in “한국미용학회지” This study found that gene expression changes in hair bulb cells are linked to graying hair, affecting processes like melanogenesis and cell-cell interaction.
December 2010 in “Elsevier eBooks” This article discusses the clinical manifestations of systemic lupus erythematosus and their potential mechanisms, but reports no new experimental results.
December 2010 in “Jurnal Natural (Faculty of Mathematics and Natural Science, Syiah Kuala University)” This thesis explores both environmental and genetic factors in prostate cancer, focusing on surrogate hormone markers, medical radiation, family history, and genetic polymorphisms related to DNA repair and hormone marker genes, but reports no new clinical findings.
February 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This research identified fluphenazine as a novel agent that induced hair growth in mice, with iloprost further enhancing this effect, through gene expression analysis and connectivity mapping.
January 2010 in “Yearbook of Endocrinology” Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
December 2009 in “Expert review of dermatology” This article reviews evidence suggesting that vitamin D and its metabolite may help protect against nonmelanoma skin cancer, but reports no new empirical findings.
January 2009 in “OhioLink ETD Center (Ohio Library and Information Network)” This study found that p63 and p73 regulate the vitamin D receptor (VDR), with p63 influencing cancer cell behaviors and p73 playing a role in vitamin D-mediated differentiation.
January 2008 in “中山醫學大學醫學研究所學位論文” This study found that Danthron induced apoptosis in a human malignant melanoma cell line through mitochondrial, endoplasmic reticulum, and death receptor pathways.
July 2007 in “Cancer biology & therapy” In this study, researchers found that deleting the ATR gene in adult mice led to signs of premature aging and reduced capacity for tissue renewal.
This study observed that spironolactone, in various doses, did not affect the growth or DNA synthesis of human hair follicles in vitro compared to a control group.
March 2005 in “Journal of the American Academy of Dermatology” Recognizing minor skin lesions can help identify serious cancer syndromes.
January 2005 in “Pharmaceutical Journal of Chinese People's Liberation Army” In this study with cultured C_57BL/6J mouse hair follicles, ginseng extract at a concentration of 0.1 mg/ml was reported to best promote hair growth.
This study reports that melatonin influenced HaCaT cell proliferation, with high concentrations reducing DNA synthesis and low concentrations enhancing it after 24 hours.
March 1994 in “Proceedings of the British Society of Animal Production” This study investigated hair fibre growth in Angora and Cashmere goats, finding differences in growth rates and seasonal dependencies, and examined the effects of prolactin and melatonin on protein deposition in hair follicles.
February 1990 in “PubMed” This study observed that hirsute females displayed increased S-phase hair bulb cells and decreased G0/1-phase cells compared to healthy females, with a strong correlation between S-phase percentages and DHEA-S levels.
May 2022 in “The FASEB Journal” This experimental study suggests that finasteride may reduce Lymphocyte Specific Protein 1 gene expression through methylation in human Leydig cells, potentially offering a pathway for treating Neutrophil Actin Dysfunction.