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research A Study on the Utilization of Dendropanax morbifera Lev. Leaf Extract for Material of Functional Cosmetics and Hair Growth Products
In this study, the methanol-ultrasound extract of Dendropanax morbifera leaf showed potential for use in functional cosmetics and hair growth products due to its high antioxidant capacity and effects on growth factor expression without cytotoxicity.
research Comparison of the efficacy of tea tree (Melaleuca alternifolia) oil with other current pharmacological management in human demodicosis: A Systematic Review
This review found that tea tree oil, especially terpinen-4-ol, may be the most effective treatment for Demodex-related diseases, but more research is needed to improve treatment efficacy and reduce side effects.
research From Weed to Wonder: Exploring the Multifaceted Pharmacological Actions of Tridax procumbens Linn.
This review of Tridax procumbens highlights its pharmacological and phytochemical potential, noting the presence of biologically active compounds and suggesting its value as a basis for developing new plant-based therapeutics due to its diverse medicinal properties and low toxicity.
research Active Compounds with Medicinal Potential Found in Maxillariinae Benth. (Orchidaceae Juss.) Representatives—A Review
This review discusses the biologically active compounds in Maxillariinae orchids, highlighting 62 semiochemicals with medical potential, but reports no new clinical findings.
research ACTIVITY OF MEDICINALPLANTS AS IMMUNOBOOSTERS
In this review, researchers evaluated 111 studies on the biological activities and phytochemical components of the plant Tridax procumbens, emphasizing its ethnobotanical potential and the need for more research to understand its therapeutic benefits, especially in its native tropical regions.
research Investigação das atividades alelopática, fitotóxica e antioxidante de extratos e frações de Tridax procumbens L. (Asteraceae). e Ouratea spectabilis (mart. ex engl.) engl. (Ochnaceae)
This study found that extracts from Tridax procumbens and Ouratea spectabilis reduced seed germination and inhibited root and hypocotyl growth in lettuce, indicating potential allelopathic effects.
research Active Antialopecia Chemical Identification of Merremia peltata Leaves and Computational Study toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation
This study found that bufotalinin, derived from Merremia peltata leaves, may enhance hair growth by acting as a potential androgen receptor antagonist in rabbits.
research Mining Therapeutic Efficacy from Treasure Chest of Biodiversity and Chemodiversity: Pharmacophylogeny of Ranunculales Medicinal Plants
This review discusses the molecular phylogeny, chemical constituents, and therapeutic applications of medicinal plants in the Ranunculales order and reports no new clinical results.
research Molecular docking simulation studies on potent butyrylcholinesterase inhibitors obtained from microbial transformation of dihydrotestosterone
This study found that microbial transformation of dihydrotestosterone with two types of fungi produced eight metabolites, among which metabolites 5–7 were significant inhibitors of butyrylcholinesterase, suggesting potential in Alzheimer's disease management.
research Exploring the Inhibitory Potential of Phytosterols β-Sitosterol, Stigmasterol, and Campesterol on 5-Alpha Reductase Activity in the Human Prostate: An In Vitro and In Silico Approach
This study found that the phytosterols β-sitosterol, stigmasterol, and campesterol have low-to-negligible inhibitory activity against steroidal 5α-reductase type 2 compared to the synthetic inhibitor dutasteride, with β-sitosterol showing the highest activity among the tested phytosterols.
research Antioxidant activity of fractions from Tridax procumbens.
This study found that fractions of Tridax procumbens extract demonstrated significant antioxidant activity, comparable to standard ascorbic acid, in laboratory tests.
research Comprehensive Evaluationof Tectonagrandis L.f.: Integrated In Vitro and In Silico Analysis of Steroid 5α-ReductaseInhibition and Anti-Inflammatory Properties
This study found that the leaf extract of Tectona grandis and its major bioactive constituents moderately inhibit the 5α-reductase enzyme, which is linked to androgenetic alopecia, and also possess anti-inflammatory properties, showing promise as dual-action candidates for managing this condition.
research Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum
In castrated rats, this study found that triterpenoids from Ganoderma lucidum inhibited both types of 5α-reductase and reduced prostate growth linked to testosterone but not dihydrotestosterone.
research Antibacterial potential and phytochemical analysis of two ethnomedicinally important plants
This study found that extracts from the medicinal plants *Echinops echinatus* and *Tridax procumbens* displayed antimicrobial activity against several bacteria, including *Escherichia coli* and *Staphylococcus aureus*, and identified various compounds like flavonoids and terpenoids potentially responsible for these effects.
research Dependence of anxiolytic effects of the dipeptide TSPO ligand GD-23 on neurosteroid biosynthesis
This study found that GD-23, a dipeptide ligand of TSPO, exhibited an anxiolytic effect in the elevated plus maze test, which was inhibited by selective neurosteroid synthesis inhibitors, suggesting a neurosteroidogenic mechanism.
research Relative binding affinity of novel steroids to androgen receptors in hamster prostate
This study found that certain steroidal compounds, especially 10a–10c, demonstrated strong antiandrogenic activity by binding to the androgen receptor and reducing prostate weight in a hamster model.
research A Convenient Synthesis of (16S,20S)-3β-Hydroxy-5α-pregnane-20,16-carbolactam and Its N-alkyl Derivatives
This paper describes the synthesis of (16S,20S)-3β-hydroxy-5α-pregnane-20,16-carbolactam from tigogenin without presenting new experimental results.
research Impact of a Novel Dehydroepiandrosterone Derivative on the Metabolism of RWPE-1 and LNCaP Cell Lines
This research found that a novel dehydroepiandrosterone derivative (12) significantly reduces cell viability and increases apoptosis in testosterone-stimulated normal and tumor prostate cells, unlike finasteride and dutasteride, which also showed activity under dihydrotestosterone stimulation.
research Cutaneous hydroxystereoid dehydrogenases and rat-hair-cycle
Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.
research The search for bioactive compounds in tropical plants to target hormone imbalance associated diseases
This study identified Aquilaria sinensis and Piper cubeba as tropical plants with potential anti-androgenic and anti-estrogenic properties that could help prevent or alleviate benign prostatic hyperplasia and prostate cancer.
research PTP1B Inhibitory and Anti-inflammatory Properties of Constituents from Eclipta prostrata L.
This study found that certain fatty acids and triterpenoid-glycosides from Eclipta prostrata L. leaves exhibit potent inhibitory effects on the protein tyrosine phosphatase 1B enzyme, suggesting potential anti-diabetic and anti-obesity benefits.
research Computer Based Screening of Selected Phytoconstituents from Cyperus Rotundus Linn. Against 5 α Reductase Enzyme
This study found that humulen, a phytoconstituent of Cyperus Rotundus Linn., showed the highest binding affinity in molecular docking with the 5 α reductase enzyme, suggesting potential anti-androgenic effects for hirsutism treatment.
research Anti-androgenic effect of sesquiterpenes isolated from the rhizomes of Curcuma aeruginosa Roxb.
In this study, germacrone from Curcuma aeruginosa showed anti-androgenic effects by inhibiting 5α-reductase, suggesting its potential as a lead compound for treating androgen-dependent disorders.
research Mechanisms of Puerariae Lobatae Radix in regulating sebaceous gland secretion: insights from network pharmacology and experimental validation
This study demonstrates that Puerariae Lobatae Radix may regulate skin lipid metabolism by inhibiting sebaceous gland growth and reducing triglyceride secretion, highlighting its therapeutic potential for sebaceous gland-related conditions.
research Investigating bioactive phytochemicals in bulb and shoot of Allium longisepalum Bertol. from Iran
This study analyzed the bioactive compound profiles of Allium longisepalum from Iran, finding unique metabolites with potential antioxidant, allelopathic, antibacterial, anti-inflammatory, anticarcinogenic, and hair growth-enhancing properties, revealing the plant's chemical diversity and therapeutic potential.
research Antioxidant activity of various solvent extracts from endophytic bacteria isolated from girang (Leea indica) leaves
This study found that endophytic bacteria isolated from Leea indica leaves showed high antioxidant activity, suggesting they could be a novel source of natural antioxidants.
research Nghiên cứu thành phần hóa học của dược liệu Cỏ bắc (Leersia hexandra Sw., Poaceae)
This study isolated and identified three natural compounds—syringaresinol, mayuenolid, and ciwujiaton—from Leersia hexandra, a traditional liver treatment used in Huyện Tam Nông, Đồng Tháp, using advanced chromatography and spectroscopy techniques.
research 498 Innate immunity activation of sebocyte cells by living bacteria. Evidence of a potential immunosuppressive effect of DHT
The researchers reported that DHT may reduce the inflammatory responses induced by C. acnes in androgen-sensitive human sebocyte cells, suggesting a potential link between androgens and infection in sebaceous disorders.
research A Concise Review on Biological Activity of Tridax procumbens Linn
This article reviews the traditional uses and documented properties of Tridax procumbens in medicine but reports no original research findings, emphasizing its potential therapeutic applications.